Primäres Plattenepithelkarzinom der Gallenblase als seltene Ursache für eine akute Cholezystitis = Acute squamous cell carcinoma of the gallbladder - a rare cause of acute cholecystitis

History and admission findings: A 54-year-old woman with signs of acute cholecystitis but no other relevant diseases was admitted into our hospital. Investigations: The abdominal ultrasonography showed an acute cholecystitis with possibly an abscess in the bed of the gallbladder (DD gall bladder can...

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Main Authors: Damian, Ulrich (Author) , Rumstadt, Bernhard (Author) , Schilling, Dieter (Author)
Format: Article (Journal)
Language:German
Published: 28. Juni 2011
In: Deutsche medizinische Wochenschrift
Year: 2011, Volume: 136, Issue: 27, Pages: 1422-1425
ISSN:1439-4413
DOI:10.1055/s-0031-1281531
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0031-1281531
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0031-1281531
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Author Notes:U. Damian, B. Rumstadt, D. Schilling

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520 |a History and admission findings: A 54-year-old woman with signs of acute cholecystitis but no other relevant diseases was admitted into our hospital. Investigations: The abdominal ultrasonography showed an acute cholecystitis with possibly an abscess in the bed of the gallbladder (DD gall bladder cancer). Therefore a laparoscopy was performed which revealed a tumorous infiltrating the adjacent organs. A R1 resection was performed. Diagnosis, treatment and course: The histological examination revealed the rare finding of a squamous cell cancer of the gall bladder. On advice of our tumor board, chemotherapy with cisplatin and 5-flourouracil was initiated. Tumor-associated bile duct stenosis required endoscopic stent implantation. Despite the poor prognosis the disease remained stable 18 month later, with a Karnofsky index of 100%.Conclusion: Squamous cell carcinoma of the gallbladder is rare and requires a good interdisciplinary management. In an individual setting it is possible to increase survival with interdisciplinary treatment and palliative chemotherapy. 
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