Governing the invasive trophoblast: current aspects on intra- and extracellular regulation
Citation Fitzgerald JS, Germeyer A, Huppertz B, Jeschke U, Knöfler M, Moser G, Scholz C, Sonderegger S, Toth B, Markert UR. Governing the invasive trophoblast: current aspects on intra- and extracellular regulation. Am J Reprod Immunol 2010 This review summarizes several aspects especially of regul...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
10 May 2010
|
| In: |
American journal of reproductive immunology
Year: 2010, Jahrgang: 63, Heft: 6, Pages: 492-505 |
| ISSN: | 1600-0897 |
| DOI: | 10.1111/j.1600-0897.2010.00824.x |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1111/j.1600-0897.2010.00824.x Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0897.2010.00824.x 
|
| Verfasserangaben: | Justine S. Fitzgerald, Ariane Germeyer, Berthold Huppertz, Udo Jeschke, Martin Knöfler, Gerit Moser, Christoph Scholz, Stefan Sonderegger, Bettina Toth, Udo R. Markert |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1844851567 | ||
| 003 | DE-627 | ||
| 005 | 20230710135238.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230509s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/j.1600-0897.2010.00824.x |2 doi | |
| 035 | |a (DE-627)1844851567 | ||
| 035 | |a (DE-599)KXP1844851567 | ||
| 035 | |a (OCoLC)1389805782 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Fitzgerald, Justine Sayuri |d 1973- |e VerfasserIn |0 (DE-588)133574598 |0 (DE-627)691594449 |0 (DE-576)299943593 |4 aut | |
| 245 | 1 | 0 | |a Governing the invasive trophoblast |b current aspects on intra- and extracellular regulation |c Justine S. Fitzgerald, Ariane Germeyer, Berthold Huppertz, Udo Jeschke, Martin Knöfler, Gerit Moser, Christoph Scholz, Stefan Sonderegger, Bettina Toth, Udo R. Markert |
| 264 | 1 | |c 10 May 2010 | |
| 300 | |a 14 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 09.05.2023 | ||
| 520 | |a Citation Fitzgerald JS, Germeyer A, Huppertz B, Jeschke U, Knöfler M, Moser G, Scholz C, Sonderegger S, Toth B, Markert UR. Governing the invasive trophoblast: current aspects on intra- and extracellular regulation. Am J Reprod Immunol 2010 This review summarizes several aspects especially of regulating factors governing trophoblast invasion. Those include the composition of the extracellular matrix containing a variety of matrix metalloproeinases and their inhibitors, but also intracellular signals. Furthermore, a newly described trophoblast subtype, the endoglandular trophoblast, is presented. Its presence may provide a possible mechanism for opening and connecting uterine glands into the intervillous space. Amongst others, two intracellular signalling pathways are crucial for regulation of trophoblast functions and development: Wnt- and signal transducer and activator of transcription (STAT)3 signalling. Wnt signalling promotes implantation, placentation and trophoblast differentiation. Several Wnt-dependent cascades and regulatory mechanisms display different functions in trophoblast cells. The STAT3 signalling system is fundamental for induction and regulation of invasiveness in physiological trophoblastic cells, but also in tumours. The role of galectins (Gal) in trophoblast regulation and placenta development comes increasingly into focus. The Gal- 1-4, 7-10 and 12-14 have been detected in humans. Detailed information is only available for Gal-1, -2, -3, -4, -9 and -12 in endometrium and decidua. Gal-1, -3 and -13 (-14) have been detected and studied in trophoblast cells. | ||
| 650 | 4 | |a Decidua | |
| 650 | 4 | |a galectins | |
| 650 | 4 | |a matrix metalloproteinases | |
| 650 | 4 | |a signal transducer and activator of transcription 3 | |
| 650 | 4 | |a tissue inhibitors of metalloproteinases | |
| 650 | 4 | |a trophoblast cells | |
| 650 | 4 | |a Wnt signalling | |
| 700 | 1 | |a Germeyer, Ariane |d 1973- |e VerfasserIn |0 (DE-588)122985788 |0 (DE-627)706117697 |0 (DE-576)293507856 |4 aut | |
| 700 | 1 | |a Huppertz, Berthold |d 1963- |e VerfasserIn |0 (DE-588)123112966 |0 (DE-627)706167244 |0 (DE-576)293561478 |4 aut | |
| 700 | 1 | |a Jeschke, Udo |d 1963- |e VerfasserIn |0 (DE-588)128637145 |0 (DE-627)376940948 |0 (DE-576)297253093 |4 aut | |
| 700 | 1 | |a Knöfler, Martin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Moser, Gerit |e VerfasserIn |4 aut | |
| 700 | 1 | |a Scholz, Christoph |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sonderegger, Stefan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Toth, Bettina |d 1971- |e VerfasserIn |0 (DE-588)115537457 |0 (DE-627)691388032 |0 (DE-576)177266228 |4 aut | |
| 700 | 1 | |a Markert, Udo R. |d 1964- |e VerfasserIn |0 (DE-588)113616759 |0 (DE-627)691189854 |0 (DE-576)28976856X |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t American journal of reproductive immunology |d Oxford : Wiley Blackwell, 1980 |g 63(2010), 6, Seite 492-505 |h Online-Ressource |w (DE-627)320637662 |w (DE-600)2024667-5 |w (DE-576)09120528X |x 1600-0897 |7 nnas |a Governing the invasive trophoblast current aspects on intra- and extracellular regulation |
| 773 | 1 | 8 | |g volume:63 |g year:2010 |g number:6 |g pages:492-505 |g extent:14 |a Governing the invasive trophoblast current aspects on intra- and extracellular regulation |
| 856 | 4 | 0 | |u https://doi.org/10.1111/j.1600-0897.2010.00824.x |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0897.2010.00824.x |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230509 | ||
| 993 | |a Article | ||
| 994 | |a 2010 | ||
| 998 | |g 115537457 |a Toth, Bettina |m 115537457:Toth, Bettina |d 910000 |d 910400 |e 910000PT115537457 |e 910400PT115537457 |k 0/910000/ |k 1/910000/910400/ |p 9 | ||
| 998 | |g 122985788 |a Germeyer, Ariane |m 122985788:Germeyer, Ariane |d 910000 |d 910400 |e 910000PG122985788 |e 910400PG122985788 |k 0/910000/ |k 1/910000/910400/ |p 2 | ||
| 999 | |a KXP-PPN1844851567 |e 431989247X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"id":{"doi":["10.1111/j.1600-0897.2010.00824.x"],"eki":["1844851567"]},"name":{"displayForm":["Justine S. Fitzgerald, Ariane Germeyer, Berthold Huppertz, Udo Jeschke, Martin Knöfler, Gerit Moser, Christoph Scholz, Stefan Sonderegger, Bettina Toth, Udo R. Markert"]},"recId":"1844851567","physDesc":[{"extent":"14 S."}],"title":[{"title_sort":"Governing the invasive trophoblast","title":"Governing the invasive trophoblast","subtitle":"current aspects on intra- and extracellular regulation"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"note":["Gesehen am 09.05.2023"],"origin":[{"dateIssuedKey":"2010","dateIssuedDisp":"10 May 2010"}],"relHost":[{"disp":"Governing the invasive trophoblast current aspects on intra- and extracellular regulationAmerican journal of reproductive immunology","physDesc":[{"extent":"Online-Ressource"}],"recId":"320637662","type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"note":["Gesehen am 23.03.22"],"title":[{"title":"American journal of reproductive immunology","title_sort":"American journal of reproductive immunology","subtitle":"official journal of the American Society for Reproductive Immunology"}],"origin":[{"publisher":"Wiley Blackwell ; Blackwell Munksgaard","dateIssuedKey":"1980","publisherPlace":"Oxford ; Oxford","dateIssuedDisp":"1980-"}],"id":{"eki":["320637662"],"issn":["1600-0897"],"doi":["10.1111/(ISSN)1600-0897"],"zdb":["2024667-5"]},"part":{"year":"2010","volume":"63","pages":"492-505","extent":"14","text":"63(2010), 6, Seite 492-505","issue":"6"},"corporate":[{"display":"American Society for the Immunology of Reproduction","role":"isb"}],"pubHistory":["1.1980/81 -"]}],"person":[{"family":"Fitzgerald","given":"Justine Sayuri","role":"aut","display":"Fitzgerald, Justine Sayuri"},{"role":"aut","given":"Ariane","family":"Germeyer","display":"Germeyer, Ariane"},{"display":"Huppertz, Berthold","family":"Huppertz","given":"Berthold","role":"aut"},{"given":"Udo","role":"aut","family":"Jeschke","display":"Jeschke, Udo"},{"display":"Knöfler, Martin","family":"Knöfler","given":"Martin","role":"aut"},{"family":"Moser","role":"aut","given":"Gerit","display":"Moser, Gerit"},{"display":"Scholz, Christoph","family":"Scholz","given":"Christoph","role":"aut"},{"family":"Sonderegger","given":"Stefan","role":"aut","display":"Sonderegger, Stefan"},{"family":"Toth","role":"aut","given":"Bettina","display":"Toth, Bettina"},{"given":"Udo R.","role":"aut","family":"Markert","display":"Markert, Udo R."}]} | ||
| SRT | |a FITZGERALDGOVERNINGT1020 | ||