First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases

Despite progress in treatment, progressive non-small cell lung cancer (NSCLC) still limits survival dramatically, and novel therapeutic compounds are needed. Initial investigations suggest that artesunate (ART), an antimalarial drug, has antiproliferative capacities. However, antiinvasive and antime...

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Main Authors: Rasheed, Suhail Ahmed Kabeer (Author) , Efferth, Thomas (Author) , Asangani, Irfan A. (Author) , Allgayer, Heike (Author)
Format: Article (Journal)
Language:English
Published: 19 July 2010
In: International journal of cancer
Year: 2010, Volume: 127, Issue: 6, Pages: 1475-1485
ISSN:1097-0215
DOI:10.1002/ijc.25315
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ijc.25315
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.25315
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Author Notes:Suhail Ahmed Kabeer Rasheed, Thomas Efferth, Irfan Ahmed Asangani and Heike Allgayer
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First evidence that the anti-malarial drug Artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases by Rasheed, Suhail Ahmed Kabeer (Author)

2010

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