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Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis

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In the pathogenesis of nonalcoholic fatty liver disease, accumulation of lipids in hepatocytes and hepatocyte apoptosis are strongly implicated in disease progression from the potentially reversible condition of steatosis to severe acute and chronic liver injury. Acyl-CoA synthetase 5, a member of t...

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Main Authors: Reinartz, Andrea (Author) , Ehling, Josef (Author) , Leue, Andrea (Author) , Liedtke, Christian (Author) , Schneider, Ursula (Author) , Kopitz, Jürgen (Author) , Weiss, Thomas (Author) , Hellerbrand, Claus (Author) , Weiskirchen, Ralf (Author) , Knüchel, Ruth (Author) , Gassler, Nikolaus (Author)
Format: Article (Journal)
Language:English
Published: 12 May 2010
In: Biochimica et biophysica acta. Molecular and cell biology of lipids
Year: 2010, Volume: 1801, Issue: 9, Pages: 1025-1035
ISSN:1879-2618
DOI:10.1016/j.bbalip.2010.04.010
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.bbalip.2010.04.010
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1388198110000892
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Author Notes:Andrea Reinartz, Josef Ehling, Andrea Leue, Christian Liedtke, Ursula Schneider, Jürgen Kopitz, Thomas Weiss, Claus Hellerbrand, Ralf Weiskirchen, Ruth Knüchel, Nikolaus Gassler
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TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas by Klaus, Christina (Author) , Schnölzer, Martina (Author) , Kopitz, Jürgen (Author) ,


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