Efficient photoactivation of a Diels-Alderase ribozyme

Here we report the first example of a photoactivatable ribozyme which catalyzes a bimolecular reaction of two small organic molecules with multiple turnover, under control of a photo-cleavable protecting group by exploiting the structural significance of a single hydrogen bond.

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Bibliographic Details
Main Authors: Nierth, Alexander (Author) , Singer, Marco (Author) , Jäschke, Andres (Author)
Format: Article (Journal) Editorial
Language:English
Published: 27 Sep 2010
In: Chemical communications
Year: 2010, Volume: 46, Issue: 42, Pages: 7975-7977
ISSN:1364-548X
DOI:10.1039/C0CC03162C
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1039/C0CC03162C
Verlag, lizenzpflichtig, Volltext: https://pubs.rsc.org/en/content/articlelanding/2010/cc/c0cc03162c
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Author Notes:Alexander Nierth, Marco Singer and Andres Jäschke
Description
Summary:Here we report the first example of a photoactivatable ribozyme which catalyzes a bimolecular reaction of two small organic molecules with multiple turnover, under control of a photo-cleavable protecting group by exploiting the structural significance of a single hydrogen bond.
Item Description:Gesehen am 17.05.2023
Physical Description:Online Resource
ISSN:1364-548X
DOI:10.1039/C0CC03162C