Buchumschlag

Axial length and choriocapillaris flow deficits in non-pathological high myopia

Purpose - To examine the relationship between axial length (AL) and choriocapillaris (CC) flow deficits percentage (FD%) in non-pathological highly myopic eyes. - Design - Prospective cross-sectional study. - Methods - This study included Chinese patients with non-pathological high myopia, which was...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cheng, Weijing (VerfasserIn) , Song, Yunhe (VerfasserIn) , Gao, Xinbo (VerfasserIn) , Lin, Fengbin (VerfasserIn) , Li, Fei (VerfasserIn) , Wang, Peiyuan (VerfasserIn) , Hu, Kun (VerfasserIn) , Li, Hao (VerfasserIn) , Li, Yingjie (VerfasserIn) , Chen, Lina (VerfasserIn) , Jonas, Jost B. (VerfasserIn) , Wang, Wei (VerfasserIn) , Zhang, Xiulan (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 12 August 2022
In: American journal of ophthalmology
Year: 2022, Jahrgang: 244, Pages: 68-78
ISSN:1879-1891
DOI:10.1016/j.ajo.2022.08.005
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ajo.2022.08.005
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0002939422003099
Volltext
Verfasserangaben:Weijing Cheng, Yunhe Song, Xinbo Gao, Fengbin Lin, Fei Li, Peiyuan Wang, Kun Hu, Hao Li, Yingjie Li, Lina Chen, Jost B. Jonas, Wei Wang, and Xiulan Zhang
Beschreibung
Zusammenfassung:Purpose - To examine the relationship between axial length (AL) and choriocapillaris (CC) flow deficits percentage (FD%) in non-pathological highly myopic eyes. - Design - Prospective cross-sectional study. - Methods - This study included Chinese patients with non-pathological high myopia, which was defined by an AL of > 26 mm and a META-PM classification grade of <2. Swept-source optical coherence tomography angiography was used to obtain 6 × 6 mm images of the macular CC. The CC FD% was measured in the fovea, parafovea, and perifovea subfields. - Results - A total of 1017 individuals (1017 eyes) with a mean age of 35.95 ± 14.11 years were included. After adjusting for age, sex, intraocular pressure, body mass index, systolic blood pressure, and image quality score, the overall CC FD% increased by 0.27% (95% CI 0.02, 0.52; P = .034) for each mm increase in AL. Among subfields, longer AL was associated with a higher CC FD% in the perifovea (β = 0.53, 95% CI 0.30, 0.77; P < .001), and was not associated with a higher CC FD% in the parafovea (β = 0.08, 95% CI -0.26, 0.42; P = .652) and fovea (β = 0.001, 95% CI -0.50, 0.50; P = .999). - Conclusions - The CC FD% increased with a longer AL in high myopia in the perifovea region but not in the fovea and parafovea fields. These findings may be of interest in elucidating the etiology of myopic axial elongation.
Beschreibung:Gesehen am 23.05.2023
Beschreibung:Online Resource
ISSN:1879-1891
DOI:10.1016/j.ajo.2022.08.005

Ähnliche Einträge