The need for a subsequent transvenous system in patients implanted with subcutaneous implantable cardioverter-defibrillator

Background - The absence of pacing capabilities may reduce the appeal of subcutaneous implantable cardioverter-defibrillator (S-ICD) devices for patients at risk for conduction disorders or with antitachycardia pacing (ATP)/cardiac resynchronization (CRT) requirements. Reports of rates of S-ICD to t...

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Hauptverfasser: Gasperetti, Alessio (VerfasserIn) , Schiavone, Marco (VerfasserIn) , Vogler, Julia (VerfasserIn) , Laredo, Mikael (VerfasserIn) , Fastenrath, Fabian (VerfasserIn) , Palmisano, Pietro (VerfasserIn) , Ziacchi, Matteo (VerfasserIn) , Angeletti, Andrea (VerfasserIn) , Mitacchione, Gianfranco (VerfasserIn) , Kaiser, Lukas (VerfasserIn) , Compagnucci, Paolo (VerfasserIn) , Breitenstein, Alexander (VerfasserIn) , Arosio, Roberto (VerfasserIn) , Vitali, Francesco (VerfasserIn) , De Bonis, Silvana (VerfasserIn) , Picarelli, Francesco (VerfasserIn) , Casella, Michela (VerfasserIn) , Santini, Luca (VerfasserIn) , Pignalberi, Carlo (VerfasserIn) , Lavalle, Carlo (VerfasserIn) , Pisanò, Ennio (VerfasserIn) , Ricciardi, Danilo (VerfasserIn) , Calò, Leonardo (VerfasserIn) , Curnis, Antonio (VerfasserIn) , Bertini, Matteo (VerfasserIn) , Gulletta, Simone (VerfasserIn) , Dello Russo, Antonio (VerfasserIn) , Badenco, Nicolas (VerfasserIn) , Tondo, Claudio (VerfasserIn) , Kuschyk, Jürgen (VerfasserIn) , Tilz, Roland (VerfasserIn) , Forleo, Giovanni B. (VerfasserIn) , Biffi, Mauro (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 28 November 2022
In: Heart rhythm
Year: 2022, Jahrgang: 19, Heft: 12, Pages: 1958-1964
ISSN:1556-3871
DOI:10.1016/j.hrthm.2022.06.030
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.hrthm.2022.06.030
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S1547527122021592
Volltext
Verfasserangaben:Alessio Gasperetti, Marco Schiavone, Julia Vogler, Mikael Laredo, Fabian Fastenrath, Pietro Palmisano, Matteo Ziacchi, Andrea Angeletti, Gianfranco Mitacchione, Lukas Kaiser, Paolo Compagnucci, Alexander Breitenstein, Roberto Arosio, Francesco Vitali, Silvana De Bonis, Francesco Picarelli, Michela Casella, Luca Santini, Carlo Pignalberi, Carlo Lavalle, Ennio Pisanò, Danilo Ricciardi, Leonardo Calò, Antonio Curnis, Matteo Bertini, Simone Gulletta, Antonio Dello Russo, Nicolas Badenco, Claudio Tondo, Jürgen Kuschyk, Roland Tilz, Giovanni B. Forleo, Mauro Biffi

MARC

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245 1 4 |a The need for a subsequent transvenous system in patients implanted with subcutaneous implantable cardioverter-defibrillator  |c Alessio Gasperetti, Marco Schiavone, Julia Vogler, Mikael Laredo, Fabian Fastenrath, Pietro Palmisano, Matteo Ziacchi, Andrea Angeletti, Gianfranco Mitacchione, Lukas Kaiser, Paolo Compagnucci, Alexander Breitenstein, Roberto Arosio, Francesco Vitali, Silvana De Bonis, Francesco Picarelli, Michela Casella, Luca Santini, Carlo Pignalberi, Carlo Lavalle, Ennio Pisanò, Danilo Ricciardi, Leonardo Calò, Antonio Curnis, Matteo Bertini, Simone Gulletta, Antonio Dello Russo, Nicolas Badenco, Claudio Tondo, Jürgen Kuschyk, Roland Tilz, Giovanni B. Forleo, Mauro Biffi 
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520 |a Background - The absence of pacing capabilities may reduce the appeal of subcutaneous implantable cardioverter-defibrillator (S-ICD) devices for patients at risk for conduction disorders or with antitachycardia pacing (ATP)/cardiac resynchronization (CRT) requirements. Reports of rates of S-ICD to transvenous implantable cardioverter-defibrillator (TV-ICD) system switch in real-world scenarios are limited. - Objective - The purpose of this study was to investigate the need for a subsequent transvenous (TV) device in patients implanted with an S-ICD and its predictors. - Methods - All patients implanted with an S-ICD were enrolled from the multicenter, real-world iSUSI (International SUbcutaneouS Implantable cardioverter defibrillator) Registry. The need for a TV device and its clinical reason, and appropriate and inappropriate device therapies were assessed. Logistic regression with Firth penalization was used to assess the association between baseline and procedural characteristics and the overall need for a subsequent TV device. - Results - A total of 1509 patients were enrolled (age 50.8 ± 15.8 years; 76.9% male; 32.0% ischemic; left ventricular ejection fraction 38% [30%-60%]). Over 26.5 [13.4-42.9] months, 155 (10.3%) and 144 (9.3%) patients experienced appropriate and inappropriate device therapies, respectively. Forty-one patients (2.7%) required a TV device (13 bradycardia; 10 need for CRT; 10 inappropriate shocks). Body mass index (BMI) >30 kg/m2 and chronic kidney disease (CKD) were associated with need for a TV device (odds ratio [OR] 2.57 [1.37-4.81], P = .003; and OR 2.67 [1.29-5.54], P = .008, respectively). - Conclusion - A low rate (2.7%) of conversion from S-ICD to a TV device was observed at follow-up, with need for antibradycardia pacing, ATP, or CRT being the main reasons. BMI >30 kg/m2 and CKD predicted all-cause need for a TV device. 
650 4 |a Need for antitachycardia pacing 
650 4 |a Subcutaneous implantable cardioverter-defibrillator 
650 4 |a Subcutaneous implantable cardioverter-defibrillator complications 
650 4 |a Sudden cardiac death 
650 4 |a Transvenous implantable cardioverter-defibrillator upgrade 
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