Single nucleotide polymorphisms in matrix metalloproteinase genes and lung cancer chemotherapy response and prognosis
The prognosis for lung cancer patients treated with chemotherapy is poor. Single nucleotide polymorphisms (SNPs) in matrix metalloproteinase (MMP) genes could influence treatment outcome by altering apoptotic pathways. Eight SNPs with known or suspected phenotypic effect in six genes (MMP1, MMP2, MM...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2010
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| In: |
The European respiratory journal
Year: 2010, Jahrgang: 35, Heft: 2, Pages: 381-390 |
| ISSN: | 1399-3003 |
| DOI: | 10.1183/09031936.00125608 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1183/09031936.00125608 Verlag, lizenzpflichtig, Volltext: https://erj.ersjournals.com/content/35/2/381 
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| Verfasserangaben: | D.B. Scherf, H. Dally, P. Müller, G. Werle-Schneider, B. Jäger, L. Edler, S. Tuengerthal, J.R. Fischer, P. Drings, H. Bartsch and A. Risch |
MARC
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| 520 | |a The prognosis for lung cancer patients treated with chemotherapy is poor. Single nucleotide polymorphisms (SNPs) in matrix metalloproteinase (MMP) genes could influence treatment outcome by altering apoptotic pathways. Eight SNPs with known or suspected phenotypic effect in six genes (MMP1, MMP2, MMP3, MMP7, MMP9 and MMP12) were investigated. | ||
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