ER stress and slit diaphragms: is there a connection?
Galloway-Mowat syndrome is a neurorenal syndrome that has been linked with defective transfer RNA and protein translation caused by variants in the multiprotein complex KEOPS. In the kidney, this syndrome seems to primarily affect the podocytes, but the pathogenesis has remained unclear. In this iss...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
19 April 2023
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| In: |
Kidney international
Year: 2023, Volume: 103, Issue: 5, Pages: 830-832 |
| ISSN: | 1523-1755 |
| DOI: | 10.1016/j.kint.2023.01.028 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.kint.2023.01.028 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S008525382300145X 
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| Author Notes: | Tobias Hermle and Matias Simons |
| Summary: | Galloway-Mowat syndrome is a neurorenal syndrome that has been linked with defective transfer RNA and protein translation caused by variants in the multiprotein complex KEOPS. In the kidney, this syndrome seems to primarily affect the podocytes, but the pathogenesis has remained unclear. In this issue of Kidney International, Krausel et al. use Drosophila nephrocytes to link endoplasmic reticulum stress with defects in the slit diaphragm. |
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| Item Description: | Gesehen am 12.06.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1523-1755 |
| DOI: | 10.1016/j.kint.2023.01.028 |