Spontaneous bacterial peritonitis caused by Listeria monocytogenes: a rare infection with very high leukocyte counts in ascitic fluid-case report and review of the literature

We present a rare case of Listeria monocytogenes-induced spontaneous bacterial peritonitis (SBP) in cirrhosis. Examination of the patient's peritoneal fluid revealed an extremely high leukocyte count. We suspect, that the patient belongs to 1% of individuals in which Listeria monocytogenes is p...

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Main Authors: Meurer, Amelie Johanna (Author) , Antoni, Christoph Helmer (Author) , Ebert, Matthias (Author) , Trimborn, Anna (Author) , Hirth, Michael (Author)
Format: Article (Journal)
Language:English
Published: 29 April 2023
In: Clinics and research in hepatology and gastroenterology
Year: 2023, Volume: 47, Issue: 6, Pages: 1-5
ISSN:2210-741X
DOI:10.1016/j.clinre.2023.102130
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.clinre.2023.102130
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2210740123000554
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Author Notes:Amelie Meurer, Christoph Antoni, Matthias P. Ebert, Anna Trimborn, Michael Hirth

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520 |a We present a rare case of Listeria monocytogenes-induced spontaneous bacterial peritonitis (SBP) in cirrhosis. Examination of the patient's peritoneal fluid revealed an extremely high leukocyte count. We suspect, that the patient belongs to 1% of individuals in which Listeria monocytogenes is part of the intestinal flora. Cephalosporins as empiric antibiotics have a Listeria gap. A combination of aminopenicillin and aminoglycoside is recommended. Therefore, early microbiological diagnosis from ascites and blood is essential. Listeria should be considered as a rare cause of SBP, especially in case of very high leukocyte count in peritoneal fluid or lack of response to empiric therapy. 
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