A neuro-computational social learning framework to facilitate transdiagnostic classification and treatment across psychiatric disorders

Social deficits are among the core and most striking psychiatric symptoms, present in most psychiatric disorders. Here, we introduce a novel social learning framework, which consists of neuro-computational models that combine reinforcement learning with various types of social knowledge structures....

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Hauptverfasser: Rosenblau, Gabriela (VerfasserIn) , Frolichs, Koen (VerfasserIn) , Korn, Christoph W. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 22 April 2023
In: Neuroscience & biobehavioral reviews
Year: 2023, Jahrgang: 149, Pages: 1-20
ISSN:1873-7528
DOI:10.1016/j.neubiorev.2023.105181
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.neubiorev.2023.105181
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0149763423001501
Volltext
Verfasserangaben:Gabriela Rosenblau, Koen Frolichs, Christoph W. Korn

MARC

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520 |a Social deficits are among the core and most striking psychiatric symptoms, present in most psychiatric disorders. Here, we introduce a novel social learning framework, which consists of neuro-computational models that combine reinforcement learning with various types of social knowledge structures. We outline how this social learning framework can help specify and quantify social psychopathology across disorders and provide an overview of the brain regions that may be involved in this type of social learning. We highlight how this framework can specify commonalities and differences in the social psychopathology of individuals with autism spectrum disorder (ASD), personality disorders (PD), and major depressive disorder (MDD) and improve treatments on an individual basis. We conjecture that individuals with psychiatric disorders rely on rigid social knowledge representations when learning about others, albeit the nature of their rigidity and the behavioral consequences can greatly differ. While non-clinical cohorts tend to efficiently adapt social knowledge representations to relevant environmental constraints, psychiatric cohorts may rigidly stick to their preconceived notions or overly coarse knowledge representations during learning. 
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