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GMP-compliant production of (68Ga)Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor

[68Ga]Ga-NeoB is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and establish the preparation of [68Ga]Ga-NeoB using a GMP conform kit appr...

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Main Authors: Pretze, Marc (Author) , Reffert, Laura (Author) , Diehl, Steffen J. (Author) , Schönberg, Stefan (Author) , Wängler, Carmen (Author) , Hohenberger, Peter (Author) , Wängler, Björn (Author)
Format: Article (Journal)
Language:English
Published: 06 July 2021
In: EJNMMI radiopharmacy and chemistry
Year: 2021, Volume: 6, Issue: 1, Pages: 1-13
ISSN:2365-421X
DOI:10.1186/s41181-021-00137-w
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s41181-021-00137-w
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Author Notes:Marc Pretze, Laura Reffert, Steffen Diehl, Stefan O. Schönberg, Carmen Wängler, Peter Hohenberger, Björn Wängler

MARC

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