Buchumschlag

Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury

Liver ischemia/reperfusion (I/R) injury is a frequent cause of organ dysfunction. Loss of the oxygen sensor prolyl hydroxylase domain enzyme 1 (PHD1) causes tolerance of skeletal muscle to hypoxia. We assessed whether loss or short-term silencing of PHD1 could likewise induce hypoxia tolerance in he...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Schneider, Martin (VerfasserIn) , Van Geyte, Katie (VerfasserIn) , Fraisl, Peter (VerfasserIn) , Kiss, Judit (VerfasserIn) , Aragonés, Julián (VerfasserIn) , Mazzone, Massimiliano (VerfasserIn) , Mairbäurl, Heimo (VerfasserIn) , De Bock, Katrien (VerfasserIn) , Jeoung, Nam Ho (VerfasserIn) , Mollenhauer, Martin (VerfasserIn) , Georgiadou, Maria (VerfasserIn) , Bishop, Tammie (VerfasserIn) , Roncal, Carmen (VerfasserIn) , Sutherland, Andrew (VerfasserIn) , Jordan, Benedicte (VerfasserIn) , Gallez, Bernard (VerfasserIn) , Weitz, Jürgen (VerfasserIn) , Harris, Robert A. (VerfasserIn) , Maxwell, Patrick (VerfasserIn) , Baes, Myriam (VerfasserIn) , Ratcliffe, Peter (VerfasserIn) , Carmeliet, Peter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2010
In: Gastroenterology
Year: 2010, Jahrgang: 138, Heft: 3, Pages: 1143-1154.e2
ISSN:1528-0012
DOI:10.1053/j.gastro.2009.09.057
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1053/j.gastro.2009.09.057
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0016508509017521
Volltext
Verfasserangaben:Martin Schneider, Katie Van Geyte, Peter Fraisl, Judit Kiss, Julián Aragonés, Massimiliano Mazzone, Heimo Mairbäurl, Katrien De Bock, Nam Ho Jeoung, Martin Mollenhauer, Maria Georgiadou, Tammie Bishop, Carmen Roncal, Andrew Sutherland, Benedicte Jordan, Bernard Gallez, Jürgen Weitz, Robert A. Harris, Patrick Maxwell, Myriam Baes, Peter Ratcliffe, and Peter Carmeliet

MARC

LEADER 00000caa a2200000 c 4500
001 185071570X
003 DE-627
005 20230710130012.0
007 cr uuu---uuuuu
008 230621s2010 xx |||||o 00| ||eng c
024 7 |a 10.1053/j.gastro.2009.09.057  |2 doi 
035 |a (DE-627)185071570X 
035 |a (DE-599)KXP185071570X 
035 |a (OCoLC)1389793845 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Schneider, Martin  |d 1976-  |e VerfasserIn  |0 (DE-588)12390384X  |0 (DE-627)706468147  |0 (DE-576)42325037X  |4 aut 
245 1 0 |a Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury  |c Martin Schneider, Katie Van Geyte, Peter Fraisl, Judit Kiss, Julián Aragonés, Massimiliano Mazzone, Heimo Mairbäurl, Katrien De Bock, Nam Ho Jeoung, Martin Mollenhauer, Maria Georgiadou, Tammie Bishop, Carmen Roncal, Andrew Sutherland, Benedicte Jordan, Bernard Gallez, Jürgen Weitz, Robert A. Harris, Patrick Maxwell, Myriam Baes, Peter Ratcliffe, and Peter Carmeliet 
264 1 |c 2010 
300 |a 14 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Online veröffentlicht am 8. Oktober 2009 
500 |a Gesehen am 21.06.2023 
520 |a Liver ischemia/reperfusion (I/R) injury is a frequent cause of organ dysfunction. Loss of the oxygen sensor prolyl hydroxylase domain enzyme 1 (PHD1) causes tolerance of skeletal muscle to hypoxia. We assessed whether loss or short-term silencing of PHD1 could likewise induce hypoxia tolerance in hepatocytes and protect them against hepatic I/R damage. 
650 4 |a Ischemia/Reperfusion 
650 4 |a PHD1 
650 4 |a Prolyl Hydroxylase 
700 1 |a Van Geyte, Katie  |e VerfasserIn  |4 aut 
700 1 |a Fraisl, Peter  |e VerfasserIn  |4 aut 
700 1 |a Kiss, Judit  |d 1980-  |e VerfasserIn  |0 (DE-588)135702615  |0 (DE-627)693700424  |0 (DE-576)300596332  |4 aut 
700 1 |a Aragonés, Julián  |e VerfasserIn  |4 aut 
700 1 |a Mazzone, Massimiliano  |e VerfasserIn  |4 aut 
700 1 |a Mairbäurl, Heimo  |e VerfasserIn  |0 (DE-588)107812146X  |0 (DE-627)838003184  |0 (DE-576)44895110X  |4 aut 
700 1 |a De Bock, Katrien  |e VerfasserIn  |4 aut 
700 1 |a Jeoung, Nam Ho  |e VerfasserIn  |4 aut 
700 1 |a Mollenhauer, Martin  |d 1981-  |e VerfasserIn  |0 (DE-588)1030297673  |0 (DE-627)735001928  |0 (DE-576)378096117  |4 aut 
700 1 |a Georgiadou, Maria  |e VerfasserIn  |4 aut 
700 1 |a Bishop, Tammie  |e VerfasserIn  |4 aut 
700 1 |a Roncal, Carmen  |e VerfasserIn  |4 aut 
700 1 |a Sutherland, Andrew  |e VerfasserIn  |4 aut 
700 1 |a Jordan, Benedicte  |e VerfasserIn  |4 aut 
700 1 |a Gallez, Bernard  |e VerfasserIn  |4 aut 
700 1 |a Weitz, Jürgen  |e VerfasserIn  |0 (DE-588)1022345974  |0 (DE-627)716954451  |0 (DE-576)171632176  |4 aut 
700 1 |a Harris, Robert A.  |e VerfasserIn  |4 aut 
700 1 |a Maxwell, Patrick  |e VerfasserIn  |4 aut 
700 1 |a Baes, Myriam  |e VerfasserIn  |4 aut 
700 1 |a Ratcliffe, Peter  |e VerfasserIn  |4 aut 
700 1 |a Carmeliet, Peter  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Gastroenterology  |d New York, NY : Elsevier, 1949  |g 138(2010), 3 vom: März, Seite 1143-1154.e2  |h Online-Ressource  |w (DE-627)270937293  |w (DE-600)1478699-0  |w (DE-576)078590221  |x 1528-0012  |7 nnas  |a Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury 
773 1 8 |g volume:138  |g year:2010  |g number:3  |g month:03  |g pages:1143-1154.e2  |g extent:14  |a Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury 
856 4 0 |u https://doi.org/10.1053/j.gastro.2009.09.057  |x Resolving-System  |x Verlag  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.sciencedirect.com/science/article/pii/S0016508509017521  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20230621 
993 |a Article 
994 |a 2010 
998 |g 1022345974  |a Weitz, Jürgen  |m 1022345974:Weitz, Jürgen  |d 910000  |d 910200  |e 910000PW1022345974  |e 910200PW1022345974  |k 0/910000/  |k 1/910000/910200/  |p 17 
998 |g 1030297673  |a Mollenhauer, Martin  |m 1030297673:Mollenhauer, Martin  |d 50000  |e 50000PM1030297673  |k 0/50000/  |p 10 
998 |g 107812146X  |a Mairbäurl, Heimo  |m 107812146X:Mairbäurl, Heimo  |d 910000  |d 910100  |d 50000  |e 910000PM107812146X  |e 910100PM107812146X  |e 50000PM107812146X  |k 0/910000/  |k 1/910000/910100/  |k 0/50000/  |p 7 
998 |g 135702615  |a Kiss, Judit  |m 135702615:Kiss, Judit  |d 50000  |e 50000PK135702615  |k 0/50000/  |p 4 
998 |g 12390384X  |a Schneider, Martin  |m 12390384X:Schneider, Martin  |d 910000  |d 910200  |e 910000PS12390384X  |e 910200PS12390384X  |k 0/910000/  |k 1/910000/910200/  |p 1  |x j 
999 |a KXP-PPN185071570X  |e 4341181475 
BIB |a Y 
SER |a journal 
JSO |a {"language":["eng"],"name":{"displayForm":["Martin Schneider, Katie Van Geyte, Peter Fraisl, Judit Kiss, Julián Aragonés, Massimiliano Mazzone, Heimo Mairbäurl, Katrien De Bock, Nam Ho Jeoung, Martin Mollenhauer, Maria Georgiadou, Tammie Bishop, Carmen Roncal, Andrew Sutherland, Benedicte Jordan, Bernard Gallez, Jürgen Weitz, Robert A. Harris, Patrick Maxwell, Myriam Baes, Peter Ratcliffe, and Peter Carmeliet"]},"person":[{"display":"Schneider, Martin","given":"Martin","family":"Schneider","role":"aut"},{"role":"aut","family":"Van Geyte","display":"Van Geyte, Katie","given":"Katie"},{"family":"Fraisl","role":"aut","display":"Fraisl, Peter","given":"Peter"},{"family":"Kiss","role":"aut","display":"Kiss, Judit","given":"Judit"},{"role":"aut","family":"Aragonés","display":"Aragonés, Julián","given":"Julián"},{"family":"Mazzone","role":"aut","given":"Massimiliano","display":"Mazzone, Massimiliano"},{"display":"Mairbäurl, Heimo","given":"Heimo","role":"aut","family":"Mairbäurl"},{"family":"De Bock","role":"aut","display":"De Bock, Katrien","given":"Katrien"},{"given":"Nam Ho","display":"Jeoung, Nam Ho","family":"Jeoung","role":"aut"},{"family":"Mollenhauer","role":"aut","display":"Mollenhauer, Martin","given":"Martin"},{"display":"Georgiadou, Maria","given":"Maria","family":"Georgiadou","role":"aut"},{"role":"aut","family":"Bishop","display":"Bishop, Tammie","given":"Tammie"},{"display":"Roncal, Carmen","given":"Carmen","family":"Roncal","role":"aut"},{"role":"aut","family":"Sutherland","display":"Sutherland, Andrew","given":"Andrew"},{"role":"aut","family":"Jordan","display":"Jordan, Benedicte","given":"Benedicte"},{"display":"Gallez, Bernard","given":"Bernard","family":"Gallez","role":"aut"},{"role":"aut","family":"Weitz","given":"Jürgen","display":"Weitz, Jürgen"},{"display":"Harris, Robert A.","given":"Robert A.","family":"Harris","role":"aut"},{"display":"Maxwell, Patrick","given":"Patrick","family":"Maxwell","role":"aut"},{"role":"aut","family":"Baes","given":"Myriam","display":"Baes, Myriam"},{"family":"Ratcliffe","role":"aut","display":"Ratcliffe, Peter","given":"Peter"},{"given":"Peter","display":"Carmeliet, Peter","family":"Carmeliet","role":"aut"}],"recId":"185071570X","note":["Online veröffentlicht am 8. Oktober 2009","Gesehen am 21.06.2023"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"title":[{"title_sort":"Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury","title":"Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury"}],"id":{"eki":["185071570X"],"doi":["10.1053/j.gastro.2009.09.057"]},"physDesc":[{"extent":"14 S."}],"relHost":[{"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injuryGastroenterology","corporate":[{"display":"American Gastroenterological Association","role":"isb"}],"language":["eng"],"part":{"pages":"1143-1154.e2","extent":"14","issue":"3","text":"138(2010), 3 vom: März, Seite 1143-1154.e2","year":"2010","volume":"138"},"pubHistory":["Nachgewiesen 12.1949 -"],"note":["Gesehen am 21.07.25"],"title":[{"title":"Gastroenterology","subtitle":"official publication of the American Gastroenterological Association","title_sort":"Gastroenterology"}],"id":{"zdb":["1478699-0"],"eki":["270937293"],"issn":["1528-0012"]},"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedDisp":"1949-","publisher":"Elsevier ; Williams & Wilkins ; Saunders","publisherPlace":"New York, NY ; Baltimore, Md. ; Philadelphia, Pa. [u.a.]","dateIssuedKey":"1949"}],"recId":"270937293"}],"origin":[{"dateIssuedDisp":"2010","dateIssuedKey":"2010"}]} 
SRT |a SCHNEIDERMLOSSORSILE2010 

Ähnliche Einträge