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ALS-linked loss of Cyclin-F function affects HSP90

The founding member of the F-box protein family, Cyclin-F, serves as a substrate adaptor for the E3 ligase Skp1-Cul1-F-box (SCF)Cyclin-F which is responsible for ubiquitination of proteins involved in cell cycle progression, DNA damage and mitotic fidelity. Missense mutations in CCNF encoding for Cy...

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Hauptverfasser: Siebert, Alexander (VerfasserIn) , Gattringer, Vanessa (VerfasserIn) , Weishaupt, Jochen H. (VerfasserIn) , Behrends, Christian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 16 September, 2022
In: Life science alliance
Year: 2022, Jahrgang: 5, Heft: 12, Pages: 1-17
ISSN:2575-1077
DOI:10.26508/lsa.202101359
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.26508/lsa.202101359
Verlag, kostenfrei, Volltext: https://www.life-science-alliance.org/content/5/12/e202101359
Volltext
Verfasserangaben:Alexander Siebert, Vanessa Gattringer, Jochen H. Weishaupt, Christian Behrends

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