A combined ex vivo and in vivo RNAi screen for notch regulators in drosophila reveals an extensive notch interaction network

Notch signaling plays a fundamental role in cellular differentiation and has been linked to human diseases, including cancer. We report the use of comprehensive RNAi analyses to dissect Notch regulation and its connections to cellular pathways. A cell-based RNAi screen identified 900 candidate Notch...

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Bibliographic Details

Main Authors:	Saj, Abil (Author) , Arzıman Büyükboduk, Zeynep (Author) , Stempfle, Denise (Author) , Belle, Werner van (Author) , Sauder, Ursula (Author) , Horn, Thomas (Author) , Dürrenberger, Markus (Author) , Paro, Renato (Author) , Boutros, Michael (Author) , Merdes, Gunter (Author)
Format:	Article (Journal)
Language:	English
Published:	17 May 2010
In:	Developmental cell Year: 2010, Volume: 18, Issue: 5, Pages: 862-876
ISSN:	1878-1551
DOI:	10.1016/j.devcel.2010.03.013
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.devcel.2010.03.013 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1534580710001528
Author Notes:	Abil Saj, Zeynep Arziman, Denise Stempfle, Werner van Belle, Ursula Sauder, Thomas Horn, Markus Dürrenberger, Renato Paro, Michael Boutros, and Gunter Merdes