Cover Image

Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke

A number of data indicate that the lectin pathway of complement activation contributes to the pathophysiology of ischemic stroke. The lectin pathway may be triggered by the binding of mannose-binding lectin (MBL), ficolin-2 or ficolin-3 to different ligands. Although several papers demonstrated the...

Full description

Saved in:
Bibliographic Details
Main Authors: Füst, George (Author) , Munthe-Fog, Lea (Author) , Illes, Zsolt (Author) , Széplaki, Gábor (Author) , Molnar, Tihamér (Author) , Pusch, Gabriella (Author) , Hirschberg, Kristóf (Author) , Szegedi, Robert (Author) , Széplaki, Zoltán (Author) , Prohászka, Zoltán (Author) , Skjoedt, Mikkel-Ole (Author) , Garred, Peter (Author)
Format: Article (Journal)
Language:English
Published: 29 December 2011
In: Journal of neuroinflammation
Year: 2011, Volume: 8, Pages: 1-10
ISSN:1742-2094
DOI:10.1186/1742-2094-8-185
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1742-2094-8-185
Get full text
Author Notes:George Füst, Lea Munthe-Fog, Zsolt Illes, Gábor Széplaki, Tihamér Molnar, Gabriella Pusch, Kristóf Hirschberg, Robert Szegedi, Zoltán Széplaki, Zoltán Prohászka, Mikkel-Ole Skjoedt and Peter Garred
Description
Summary:A number of data indicate that the lectin pathway of complement activation contributes to the pathophysiology of ischemic stroke. The lectin pathway may be triggered by the binding of mannose-binding lectin (MBL), ficolin-2 or ficolin-3 to different ligands. Although several papers demonstrated the significance of MBL in ischemic stroke, the role of ficolins has not been examined.
Item Description:Gesehen am 03.07.2023
Physical Description:Online Resource
ISSN:1742-2094
DOI:10.1186/1742-2094-8-185

Similar Items