Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke
A number of data indicate that the lectin pathway of complement activation contributes to the pathophysiology of ischemic stroke. The lectin pathway may be triggered by the binding of mannose-binding lectin (MBL), ficolin-2 or ficolin-3 to different ligands. Although several papers demonstrated the...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
29 December 2011
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| In: |
Journal of neuroinflammation
Year: 2011, Volume: 8, Pages: 1-10 |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/1742-2094-8-185 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1742-2094-8-185 |
| Author Notes: | George Füst, Lea Munthe-Fog, Zsolt Illes, Gábor Széplaki, Tihamér Molnar, Gabriella Pusch, Kristóf Hirschberg, Robert Szegedi, Zoltán Széplaki, Zoltán Prohászka, Mikkel-Ole Skjoedt and Peter Garred |
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| 520 | |a A number of data indicate that the lectin pathway of complement activation contributes to the pathophysiology of ischemic stroke. The lectin pathway may be triggered by the binding of mannose-binding lectin (MBL), ficolin-2 or ficolin-3 to different ligands. Although several papers demonstrated the significance of MBL in ischemic stroke, the role of ficolins has not been examined. | ||
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