Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke

A number of data indicate that the lectin pathway of complement activation contributes to the pathophysiology of ischemic stroke. The lectin pathway may be triggered by the binding of mannose-binding lectin (MBL), ficolin-2 or ficolin-3 to different ligands. Although several papers demonstrated the...

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Hauptverfasser: Füst, George (VerfasserIn) , Munthe-Fog, Lea (VerfasserIn) , Illes, Zsolt (VerfasserIn) , Széplaki, Gábor (VerfasserIn) , Molnar, Tihamér (VerfasserIn) , Pusch, Gabriella (VerfasserIn) , Hirschberg, Kristóf (VerfasserIn) , Szegedi, Robert (VerfasserIn) , Széplaki, Zoltán (VerfasserIn) , Prohászka, Zoltán (VerfasserIn) , Skjoedt, Mikkel-Ole (VerfasserIn) , Garred, Peter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 29 December 2011
In: Journal of neuroinflammation
Year: 2011, Jahrgang: 8, Pages: 1-10
ISSN:1742-2094
DOI:10.1186/1742-2094-8-185
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1742-2094-8-185
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Verfasserangaben:George Füst, Lea Munthe-Fog, Zsolt Illes, Gábor Széplaki, Tihamér Molnar, Gabriella Pusch, Kristóf Hirschberg, Robert Szegedi, Zoltán Széplaki, Zoltán Prohászka, Mikkel-Ole Skjoedt and Peter Garred
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Zusammenfassung:A number of data indicate that the lectin pathway of complement activation contributes to the pathophysiology of ischemic stroke. The lectin pathway may be triggered by the binding of mannose-binding lectin (MBL), ficolin-2 or ficolin-3 to different ligands. Although several papers demonstrated the significance of MBL in ischemic stroke, the role of ficolins has not been examined.
Beschreibung:Gesehen am 03.07.2023
Beschreibung:Online Resource
ISSN:1742-2094
DOI:10.1186/1742-2094-8-185