A comparison of dacron versus flocked nylon swabs for anal cytology specimen collection
Objectives: We compared the performance of commonly used Dacron versus flocked nylon swabs for anal cytology. Study Design: From 23 HIV-positive men screened at Kaiser Permanente San Francisco (San Francisco, Calif., USA), 2 anal specimens were collected, 1 with each swab in random order, and placed...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
July 22, 2011
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| In: |
Acta cytologica
Year: 2011, Jahrgang: 55, Heft: 4, Pages: 364-367 |
| ISSN: | 1938-2650 |
| DOI: | 10.1159/000329488 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000329488
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| Verfasserangaben: | Julia C. Gage, Arpita Ghosh, Sylvia Borgonovo, Stephen Follansbee, Nicolas Wentzensen, Patti E. Gravitt, Niels Grabe, Bernd Lahrmann, Philip E. Castle |
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| 245 | 1 | 2 | |a A comparison of dacron versus flocked nylon swabs for anal cytology specimen collection |c Julia C. Gage, Arpita Ghosh, Sylvia Borgonovo, Stephen Follansbee, Nicolas Wentzensen, Patti E. Gravitt, Niels Grabe, Bernd Lahrmann, Philip E. Castle |
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| 520 | |a Objectives: We compared the performance of commonly used Dacron versus flocked nylon swabs for anal cytology. Study Design: From 23 HIV-positive men screened at Kaiser Permanente San Francisco (San Francisco, Calif., USA), 2 anal specimens were collected, 1 with each swab in random order, and placed into liquid cytology medium. Specimens were tested for cellularity by quantifying a genomic DNA (erv-3). The number of cells was assessed from prepared slides by automated image analysis. Performance was compared between swabs using 2-sample t tests and standard crossover trial analysis methods accounting for period effect. Results: Flocked swabs collected slightly more erv-3 cells than Dacron for the first sample although not significantly (p = 0.18) and a similar number of erv-3 cells for the second sample (p = 0.85). Flocked swabs collected slightly more cells per slide than the Dacron swabs at both time periods although this was only significant in the second time period (p = 0.42 and 0.03 for first and second periods, respectively). In crossover trial analysis, flocked swabs outperformed Dacron for cell count per slide based on slide imaging (p = 0.03), but Dacron and flocked swabs performed similarly based on erv-3 quantification (p = 0.14). Conclusions: Further studies should determine whether flocked swabs increase the representation of diagnostically important cells compared to Dacron. | ||
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