Acute genetic perturbation of exocyst function in the rat calyx of Held impedes structural maturation, but spares synaptic transmission

The exocyst is an octameric protein complex mediating polarized secretion by tethering vesicles to target membranes. In non-vertebrate neurons, the exocyst has been associated with constitutive membrane addition at growth cones and nerve terminals, but its function in synaptic vesicle trafficking at...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Schwenger, Darius (VerfasserIn) , Kuner, Thomas (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 08 September 2010
In: European journal of neuroscience
Year: 2010, Jahrgang: 32, Heft: 6, Pages: 974-984
ISSN:1460-9568
DOI:10.1111/j.1460-9568.2010.07391.x
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1111/j.1460-9568.2010.07391.x
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1460-9568.2010.07391.x
Volltext
Verfasserangaben:Darius B. Schwenger and Thomas Kuner

MARC

LEADER 00000caa a2200000 c 4500
001 1852331631
003 DE-627
005 20240311131346.0
007 cr uuu---uuuuu
008 230711s2010 xx |||||o 00| ||eng c
024 7 |a 10.1111/j.1460-9568.2010.07391.x  |2 doi 
035 |a (DE-627)1852331631 
035 |a (DE-599)KXP1852331631 
035 |a (OCoLC)1425876964 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 32  |2 sdnb 
100 1 |a Schwenger, Darius  |e VerfasserIn  |0 (DE-588)139538623  |0 (DE-627)611821419  |0 (DE-576)312204078  |4 aut 
245 1 0 |a Acute genetic perturbation of exocyst function in the rat calyx of Held impedes structural maturation, but spares synaptic transmission  |c Darius B. Schwenger and Thomas Kuner 
264 1 |c 08 September 2010 
300 |a 11 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 11.07.2023 
520 |a The exocyst is an octameric protein complex mediating polarized secretion by tethering vesicles to target membranes. In non-vertebrate neurons, the exocyst has been associated with constitutive membrane addition at growth cones and nerve terminals, but its function in synaptic vesicle trafficking at mammalian nerve terminals remains unclear. Here, we examined the role of the exocyst complex in immature postnatal day (P)13 and mature P21 rat calyces of Held. ... 
650 4 |a nerve terminal 
650 4 |a synapse 
650 4 |a synaptic transmission 
650 4 |a vesicle transport 
700 1 |a Kuner, Thomas  |e VerfasserIn  |0 (DE-588)1074267966  |0 (DE-627)831945397  |0 (DE-576)442234562  |4 aut 
773 0 8 |i Enthalten in  |t European journal of neuroscience  |d Oxford [u.a.] : Wiley, 1989  |g 32(2010), 6 vom: Juni, Seite 974-984  |h Online-Ressource  |w (DE-627)320443299  |w (DE-600)2005178-5  |w (DE-576)090954696  |x 1460-9568  |7 nnas  |a Acute genetic perturbation of exocyst function in the rat calyx of Held impedes structural maturation, but spares synaptic transmission 
773 1 8 |g volume:32  |g year:2010  |g number:6  |g month:06  |g pages:974-984  |g extent:11  |a Acute genetic perturbation of exocyst function in the rat calyx of Held impedes structural maturation, but spares synaptic transmission 
856 4 0 |u https://doi.org/10.1111/j.1460-9568.2010.07391.x  |x Resolving-System  |x Verlag  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1460-9568.2010.07391.x  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20230711 
993 |a Article 
994 |a 2010 
998 |g 1074267966  |a Kuner, Thomas  |m 1074267966:Kuner, Thomas  |d 50000  |d 53100  |e 50000PK1074267966  |e 53100PK1074267966  |k 0/50000/  |k 1/50000/53100/  |p 2  |y j 
998 |g 139538623  |a Schwenger, Darius  |m 139538623:Schwenger, Darius  |p 1  |x j 
999 |a KXP-PPN1852331631  |e 4352008907 
BIB |a Y 
SER |a journal 
JSO |a {"physDesc":[{"extent":"11 S."}],"note":["Gesehen am 11.07.2023"],"person":[{"family":"Schwenger","roleDisplay":"VerfasserIn","display":"Schwenger, Darius","role":"aut","given":"Darius"},{"family":"Kuner","roleDisplay":"VerfasserIn","given":"Thomas","role":"aut","display":"Kuner, Thomas"}],"origin":[{"dateIssuedDisp":"08 September 2010","dateIssuedKey":"2010"}],"relHost":[{"origin":[{"publisherPlace":"Oxford [u.a.] ; Oxford ; Oxford [u.a.]","dateIssuedDisp":"1989-","dateIssuedKey":"1989","publisher":"Wiley ; Blackwell Science ; Blackwell"}],"titleAlt":[{"title":"EJN"}],"id":{"zdb":["2005178-5"],"issn":["1460-9568"],"eki":["320443299"],"doi":["10.1111/(ISSN)1460-9568"]},"physDesc":[{"extent":"Online-Ressource"}],"note":["Gesehen am 03.05.06"],"part":{"extent":"11","issue":"6","volume":"32","year":"2010","pages":"974-984","text":"32(2010), 6 vom: Juni, Seite 974-984"},"name":{"displayForm":["European Neuroscience Association"]},"pubHistory":["1.1989 -"],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"320443299","title":[{"title":"European journal of neuroscience","title_sort":"European journal of neuroscience","subtitle":"EJN"}],"disp":"Acute genetic perturbation of exocyst function in the rat calyx of Held impedes structural maturation, but spares synaptic transmissionEuropean journal of neuroscience"}],"id":{"eki":["1852331631"],"doi":["10.1111/j.1460-9568.2010.07391.x"]},"recId":"1852331631","title":[{"title":"Acute genetic perturbation of exocyst function in the rat calyx of Held impedes structural maturation, but spares synaptic transmission","title_sort":"Acute genetic perturbation of exocyst function in the rat calyx of Held impedes structural maturation, but spares synaptic transmission"}],"name":{"displayForm":["Darius B. Schwenger and Thomas Kuner"]},"type":{"bibl":"article-journal","media":"Online-Ressource"},"language":["eng"]} 
SRT |a SCHWENGERDACUTEGENET0820