Synthetic antitumor vaccines containing MUC1 glycopeptides with two immunodominant domains: induction of a strong immune response against breast tumor tissues
A shot in the arm for cancer treatment: Two MUC1 tetanus toxoid vaccines were synthesized and induced a strong immune response in mice. The antibodies elicited by the vaccines show a high selectivity for the tumor cells in mammary carcinoma tissues and also distinguish between tumor tissues at diffe...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
September 9, 2011
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| In: |
Angewandte Chemie. International edition
Year: 2011, Jahrgang: 50, Heft: 42, Pages: 9977-9981 |
| ISSN: | 1521-3773 |
| DOI: | 10.1002/anie.201104529 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/anie.201104529 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201104529 
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| Verfasserangaben: | Nikola Gaidzik, Anton Kaiser, Danuta Kowalczyk, Ulrika Westerlind, Bastian Gerlitzki, Hans Peter Sinn, Edgar Schmitt, and Horst Kunz |
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| 520 | |a A shot in the arm for cancer treatment: Two MUC1 tetanus toxoid vaccines were synthesized and induced a strong immune response in mice. The antibodies elicited by the vaccines show a high selectivity for the tumor cells in mammary carcinoma tissues and also distinguish between tumor tissues at different stages. | ||
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