Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia

acute myeloid leukemia, leukemic stem cells, cancer stem cells, hematopoietic stem cells, cellular differentiation, AML, LSC, CSC, HSC, single-cell RNA-seq, computational biology, single-cell genomics, single-cell transcriptomics, computational method

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Main Authors: Beneyto Calabuig, Sergi (Author) , Merbach, Anne Kathrin (Author) , Kniffka, Jonas-Alexander (Author) , Antes, Magdalena (Author) , Szu-Tu, Chelsea (Author) , Rohde, Christian (Author) , Waclawiczek, Alexander (Author) , Stelmach, Patrick (Author) , Gräßle, Sarah (Author) , Pervan, Philip (Author) , Janssen, Maike (Author) , Landry, Jonathan J. M. (Author) , Benes, Vladimir (Author) , Jauch, Anna (Author) , Brough, Michaela (Author) , Bauer, Marcus (Author) , Besenbeck, Birgit (Author) , Felden, Julia (Author) , Bäumer, Sebastian (Author) , Hundemer, Michael (Author) , Sauer, Tim (Author) , Pabst, Caroline (Author) , Wickenhauser, Claudia (Author) , Angenendt, Linus (Author) , Schliemann, Christoph (Author) , Trumpp, Andreas (Author) , Haas, Simon (Author) , Scherer, Michael (Author) , Raffel, Simon (Author) , Müller-Tidow, Carsten (Author) , Velten, Lars (Author)
Format: Article (Journal)
Language:English
Published: 4 May 2023
In: Cell stem cell
Year: 2023, Volume: 30, Issue: 5, Pages: 706-721.e8
ISSN:1875-9777
DOI:10.1016/j.stem.2023.04.001
Online Access:Resolving-System, kostenfrei: https://doi.org/10.1016/j.stem.2023.04.001
Resolving-System, kostenfrei: https://doi.org/10.25673/108982
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Author Notes:Sergi Beneyto-Calabuig, Anne Kathrin Merbach, Jonas-Alexander Kniffka, Magdalena Antes, Chelsea Szu-Tu, Christian Rohde, Alexander Waclawiczek, Patrick Stelmach, Sarah Gräßle, Philip Pervan, Maike Janssen, Jonathan J. M. Landry, Vladimir Benes, Anna Jauch, Michaela Brough, Marcus Bauer, Birgit Besenbeck, Julia Felden, Sebastian Bäumer, Michael Hundemer, Tim Sauer, Caroline Pabst, Claudia Wickenhauser, Linus Angenendt, Christoph Schliemann, Andreas Trumpp, Simon Haas, Michael Scherer, Simon Raffel, Carsten Müller-Tidow, and Lars Velten
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Summary:acute myeloid leukemia, leukemic stem cells, cancer stem cells, hematopoietic stem cells, cellular differentiation, AML, LSC, CSC, HSC, single-cell RNA-seq, computational biology, single-cell genomics, single-cell transcriptomics, computational method
Item Description:Online verfügbar: 24. April 2023, Artikelversion: 4. Mai 2023
Physical Description:Online Resource
ISSN:1875-9777
DOI:10.1016/j.stem.2023.04.001