CEST imaging of the APT and ssMT predict the overall survival of patients with glioma at the first follow-up after completion of radiotherapy at 3T
Outcome prediction of patients with glioma early after the completion of radiotherapy represents a major clinical challenge. Previously, the prognostic value of chemical exchange saturation transfer (CEST) imaging has been demonstrated in patients with newly diagnosed glioma. The objective of this s...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 2023
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| In: |
Radiotherapy and oncology
Year: 2023, Volume: 184, Pages: 1-8 |
| ISSN: | 1879-0887 |
| DOI: | 10.1016/j.radonc.2023.109694 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.radonc.2023.109694 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0167814023002323 
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| Author Notes: | Nikolaus von Knebel Doeberitz, Florian Kroh, Johannes Breitling, Laila König, Srdjan Maksimovic, Svenja Graß, Sebastian Adeberg, Moritz Scherer, Andreas Unterberg, Martin Bendszus, Wolfgang Wick, Peter Bachert, Jürgen Debus, Mark E. Ladd, Heinz-Peter Schlemmer, Andreas Korzowski, Steffen Goerke, Daniel Paech |
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| 245 | 1 | 0 | |a CEST imaging of the APT and ssMT predict the overall survival of patients with glioma at the first follow-up after completion of radiotherapy at 3T |c Nikolaus von Knebel Doeberitz, Florian Kroh, Johannes Breitling, Laila König, Srdjan Maksimovic, Svenja Graß, Sebastian Adeberg, Moritz Scherer, Andreas Unterberg, Martin Bendszus, Wolfgang Wick, Peter Bachert, Jürgen Debus, Mark E. Ladd, Heinz-Peter Schlemmer, Andreas Korzowski, Steffen Goerke, Daniel Paech |
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| 520 | |a Outcome prediction of patients with glioma early after the completion of radiotherapy represents a major clinical challenge. Previously, the prognostic value of chemical exchange saturation transfer (CEST) imaging has been demonstrated in patients with newly diagnosed glioma. The objective of this study was to assess the potential of amide proton transfer (APT)-, relayed nuclear Overhauser effect (rNOE)- and semi-solid magnetization transfer (ssMT)-imaging according to Zhou et al. (APTwasym), Goerke et al. (MTRRexAPT, MTRRexNOE and MTRRexMT) and Mehrabian et al. (PeakAreaAPT, PeakAreaNOE and MTconst) for the prognostication of the overall survival (OS) of patients with glioma at the first follow-up after the completion of radiotherapy. | ||
| 650 | 4 | |a Amide proton transfer | |
| 650 | 4 | |a Chemical exchange saturation transfer MRI | |
| 650 | 4 | |a Glioma | |
| 650 | 4 | |a Overall survival | |
| 650 | 4 | |a Radiotherapy | |
| 650 | 4 | |a Semi-solid magnetization transfer | |
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