Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiation
Helical TomoTherapy® is widely used for total body irradiation as a component of conditioning regimens before allogeneic bone-marrow transplantation. However, this technique limits the maximum length of a planning target volume to 135 cm. Therefore, patients taller than 135 cm require two planning c...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
24 November 2022
|
| In: |
European journal of medical research
Year: 2022, Jahrgang: 27, Pages: 1-9 |
| ISSN: | 2047-783X |
| DOI: | 10.1186/s40001-022-00886-7 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s40001-022-00886-7 Verlag, kostenfrei, Volltext: http://eurjmedres.biomedcentral.com/articles/10.1186/s40001-022-00886-7 
|
| Verfasserangaben: | Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Thomas Müdder, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Leonard C. Schmeel and Frank A. Giordano |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1852817119 | ||
| 003 | DE-627 | ||
| 005 | 20250730163058.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230717s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/s40001-022-00886-7 |2 doi | |
| 035 | |a (DE-627)1852817119 | ||
| 035 | |a (DE-599)KXP1852817119 | ||
| 035 | |a (OCoLC)1425217114 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Köksal, Mümtaz |d 1971- |e VerfasserIn |0 (DE-588)11818377X |0 (DE-627)694742538 |0 (DE-576)178125024 |4 aut | |
| 245 | 1 | 0 | |a Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiation |c Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Thomas Müdder, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Leonard C. Schmeel and Frank A. Giordano |
| 264 | 1 | |c 24 November 2022 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 17.07.2023 | ||
| 520 | |a Helical TomoTherapy® is widely used for total body irradiation as a component of conditioning regimens before allogeneic bone-marrow transplantation. However, this technique limits the maximum length of a planning target volume to 135 cm. Therefore, patients taller than 135 cm require two planning computed tomography scans and treatment plans. The junctional target between these two treatment plans is thus a critical region for treatment planning and delivery. Here, we compare radiation coverage of the junctional target between helical and static approaches to treatment planning and delivery to determine which approach allows high quality irradiation planning and provides more robustness against patient movement. We retrospectively analyzed 10 patients who underwent total body irradiation using a static four-field box planning approach and nine patients who underwent total body irradiation using a helical planning approach. All patients were taller than 135 cm. The junctional target volume was divided into 10 slices of 1 cm thickness (JT1-JT10) for analysis. Dosimetric parameters and dose-volume histograms were compared to assess the quality of coverage of the junctional target between the helical and static planning approaches. The D50 for the total junctional target was slightly higher than the prescribed dose for both helical and static approaches, with a mean of 108.12% for the helical group and 107.81% for the static group. The mean D95 was 98.44% ± 4.19% for the helical group and 96.20% ± 4.59% for the static group. The mean homogeneity index covering the entire junctional target volume was 1.20 ± 0.04 for the helical group and 1.21 ± 0.05 for the static group. The mean homogeneity index ranged from 1.08 ± 0.01 in JT1 to 1.22 ± 0.06 in JT6 for the helical group and from 1.06 ± 0.02 in JT1 to 1.19 ± 0.05 in JT6 for the static group. There were no significant differences in parameters between helical and static groups. However, the static approach provided robustness against up to 30 mm of lateral movement of the patient. As long as TBI using helical TomoTherapy® is limited to a maximum length of 135 cm, the junctional target must be addressed during treatment planning. Our analysis shows that the static four-field box approach is viable and offers higher robustness against lateral movement of the patient than the helical approach. | ||
| 700 | 1 | |a Baumert, Jonathan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schoroth, Felix |e VerfasserIn |4 aut | |
| 700 | 1 | |a Müdder, Thomas |e VerfasserIn |4 aut | |
| 700 | 1 | |a Scafa, Davide |d 1988- |e VerfasserIn |0 (DE-588)1209514168 |0 (DE-627)1697106099 |4 aut | |
| 700 | 1 | |a Koch, David |e VerfasserIn |4 aut | |
| 700 | 1 | |a Leitzen, Christina |d 1976- |e VerfasserIn |0 (DE-588)129644161 |0 (DE-627)476242940 |0 (DE-576)297764098 |4 aut | |
| 700 | 1 | |a Sarria, Gustavo R. |e VerfasserIn |0 (DE-588)1272014541 |0 (DE-627)1820779203 |4 aut | |
| 700 | 1 | |a Schmeel, Christopher |e VerfasserIn |0 (DE-588)1049814037 |0 (DE-627)782728634 |0 (DE-576)403819407 |4 aut | |
| 700 | 1 | |a Giordano, Frank Anton |d 1980- |e VerfasserIn |0 (DE-588)136378455 |0 (DE-627)694333093 |0 (DE-576)300990529 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of medical research |d London : BioMed Central, 2000 |g 27(2022), Artikel-ID 265, Seite 1-9 |h Online-Ressource |w (DE-627)375977775 |w (DE-600)2129989-4 |w (DE-576)281687544 |x 2047-783X |7 nnas |a Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiation |
| 773 | 1 | 8 | |g volume:27 |g year:2022 |g elocationid:265 |g pages:1-9 |g extent:9 |a Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiation |
| 856 | 4 | 0 | |u https://doi.org/10.1186/s40001-022-00886-7 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u http://eurjmedres.biomedcentral.com/articles/10.1186/s40001-022-00886-7 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230717 | ||
| 993 | |a Article | ||
| 994 | |a 2022 | ||
| 998 | |g 136378455 |a Giordano, Frank Anton |m 136378455:Giordano, Frank Anton |d 60000 |d 63000 |e 60000PG136378455 |e 63000PG136378455 |k 0/60000/ |k 1/60000/63000/ |p 10 |y j | ||
| 998 | |g 1209514168 |a Scafa, Davide |m 1209514168:Scafa, Davide |d 60000 |e 60000PS1209514168 |k 0/60000/ |p 5 | ||
| 999 | |a KXP-PPN1852817119 |e 4354289547 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"id":{"doi":["10.1186/s40001-022-00886-7"],"eki":["1852817119"]},"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"London ; Munich","dateIssuedDisp":"2000-","publisher":"BioMed Central ; Holzapfel","dateIssuedKey":"2000"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["Nachgewiesen 5.2000 -"],"part":{"extent":"9","pages":"1-9","volume":"27","year":"2022","text":"27(2022), Artikel-ID 265, Seite 1-9"},"disp":"Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiationEuropean journal of medical research","title":[{"title":"European journal of medical research","subtitle":"official organ \"Deutsche AIDS-Gesellschaft\"","title_sort":"European journal of medical research"}],"language":["eng"],"corporate":[{"role":"isb","roleDisplay":"Herausgebendes Organ","display":"Deutsche Aids-Gesellschaft"}],"note":["Gesehen am 14.05.12"],"id":{"zdb":["2129989-4"],"eki":["375977775"],"issn":["2047-783X"]},"recId":"375977775"}],"recId":"1852817119","person":[{"role":"aut","roleDisplay":"VerfasserIn","family":"Köksal","display":"Köksal, Mümtaz","given":"Mümtaz"},{"given":"Jonathan","roleDisplay":"VerfasserIn","role":"aut","display":"Baumert, Jonathan","family":"Baumert"},{"given":"Felix","roleDisplay":"VerfasserIn","role":"aut","family":"Schoroth","display":"Schoroth, Felix"},{"display":"Müdder, Thomas","family":"Müdder","roleDisplay":"VerfasserIn","role":"aut","given":"Thomas"},{"given":"Davide","display":"Scafa, Davide","family":"Scafa","roleDisplay":"VerfasserIn","role":"aut"},{"given":"David","display":"Koch, David","family":"Koch","role":"aut","roleDisplay":"VerfasserIn"},{"given":"Christina","roleDisplay":"VerfasserIn","role":"aut","display":"Leitzen, Christina","family":"Leitzen"},{"given":"Gustavo R.","role":"aut","roleDisplay":"VerfasserIn","family":"Sarria","display":"Sarria, Gustavo R."},{"family":"Schmeel","display":"Schmeel, Christopher","role":"aut","roleDisplay":"VerfasserIn","given":"Christopher"},{"role":"aut","roleDisplay":"VerfasserIn","family":"Giordano","display":"Giordano, Frank Anton","given":"Frank Anton"}],"note":["Gesehen am 17.07.2023"],"language":["eng"],"name":{"displayForm":["Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Thomas Müdder, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Leonard C. Schmeel and Frank A. Giordano"]},"title":[{"title":"Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiation","title_sort":"Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiation"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"origin":[{"dateIssuedKey":"2022","dateIssuedDisp":"24 November 2022"}],"physDesc":[{"extent":"9 S."}]} | ||
| SRT | |a KOEKSALMUEHELICALVER2420 | ||