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Semiallogenic fusions of MSI+tumor cells and activated B cells induce MSI-specific T cell responses

Various strategies have been developed to transfer tumor-specific antigens into antigen presenting cells in order to induce cytotoxic T cell responses against tumor cells. One approach uses cellular vaccines based on fusions of autologous antigen presenting cells and allogeneic tumor cells. The fusi...

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Bibliographische Detailangaben
Hauptverfasser: Garbe, Yvette (VerfasserIn) , Klier, Ulrike (VerfasserIn) , Linnebacher, Michael (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 26 September 2011
In: BMC cancer
Year: 2011, Jahrgang: 11, Pages: 1-10
ISSN:1471-2407
DOI:10.1186/1471-2407-11-410
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2407-11-410
Volltext
Verfasserangaben:Yvette Garbe, Ulrike Klier and Michael Linnebacher
Beschreibung
Zusammenfassung:Various strategies have been developed to transfer tumor-specific antigens into antigen presenting cells in order to induce cytotoxic T cell responses against tumor cells. One approach uses cellular vaccines based on fusions of autologous antigen presenting cells and allogeneic tumor cells. The fusion cells combine antigenicity of the tumor cell with optimal immunostimulatory capacity of the antigen presenting cells.
Beschreibung:Gesehen am 17.07.2023
Im Titel ist das Pluszeichen "+" hochgestellt
Beschreibung:Online Resource
ISSN:1471-2407
DOI:10.1186/1471-2407-11-410

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