Experimenter familiarization is a crucial prerequisite for assessing behavioral outcomes and reduces stress in mice not only under chronic pain conditions
Rodent behavior is affected by different environmental conditions. These do not only comprise experimental and housing conditions but also familiarization with the experimenter. However, specific effects on pain-related behavior and chronic pain conditions have not been examined. Therefore, we aimed...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
09 February 2023
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| In: |
Scientific reports
Year: 2023, Jahrgang: 13, Pages: 1-14 |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-023-29052-7 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41598-023-29052-7 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41598-023-29052-7 
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| Verfasserangaben: | Daniel Segelcke, Steven R. Talbot, Rupert Palme, Carmen La Porta, Esther Pogatzki-Zahn, André Bleich & Anke Tappe-Theodor |
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| 520 | |a Rodent behavior is affected by different environmental conditions. These do not only comprise experimental and housing conditions but also familiarization with the experimenter. However, specific effects on pain-related behavior and chronic pain conditions have not been examined. Therefore, we aimed to investigate the impact of different housing conditions, using individually ventilated and standard open top cages, inverted day-night cycles, and experimenter familiarization on male mice following peripheral neuropathy using the spared nerve injury (SNI) model. ... | ||
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