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Conventional partial pancreatoduodenectomy versus an extended pancreatoduodenectomy (triangle operation) for pancreatic head cancers - study protocol for the randomised controlled TRIANGLE trial

Pancreatic ductal carcinoma (PDAC) is the fourth most frequent cause of cancer-related death in the Western world, and its incidence is rising. In patients that undergo curative resection, local recurrence (LR) is frequent. A recently described surgical technique of extended pancreatoduodenectomy (P...

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Main Authors: Heger, Patrick (Author) , Hackert, Thilo (Author) , Diener, Markus K. (Author) , Feißt, Manuel (Author) , Klose, Christina (Author) , Dörr-Harim, Colette (Author) , Möhlenbrock, Friedhelm (Author) , Büchler, Markus W. (Author) , Mihaljevic, André Leopold (Author)
Format: Article (Journal)
Language:English
Published: 2023
In: Trials
Year: 2023, Volume: 24, Pages: 1-15
ISSN:1468-6694
DOI:10.1186/s13063-023-07337-6
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13063-023-07337-6
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Author Notes:Patrick Heger, Thilo Hackert, Markus K. Diener, Manuel Feißt, Christina Klose, Colette Dörr-Harim, Friedhelm Möhlenbrock, Markus W. Büchler and André L. Mihaljevic
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Summary:Pancreatic ductal carcinoma (PDAC) is the fourth most frequent cause of cancer-related death in the Western world, and its incidence is rising. In patients that undergo curative resection, local recurrence (LR) is frequent. A recently described surgical technique of extended pancreatoduodenectomy (PD) termed the TRIANGLE operation has been proposed as a promising approach to reduce LR and improve disease-free survival in PDAC patients.
Item Description:Veröffentlicht: 30. Mai 2023
Gesehen am 24.07.2023
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-023-07337-6

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