Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance
In 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopathogenesis of NMO.
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
08 September 2010
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| In: |
Journal of neuroinflammation
Year: 2010, Jahrgang: 7, Pages: 1-8 |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/1742-2094-7-52 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1742-2094-7-52 |
| Verfasserangaben: | Sven Jarius, Diego Franciotta, Friedemann Paul, Klemens Ruprecht, Roberto Bergamaschi, Paulus S. Rommer, Reinhard Reuss, Christian Probst, Wolfgang Kristoferitsch, Klaus Peter Wandinger, Brigitte Wildemann |
| Zusammenfassung: | In 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopathogenesis of NMO. |
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| Beschreibung: | Gesehen am 26.07.2023 |
| Beschreibung: | Online Resource |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/1742-2094-7-52 |