AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance
Neuromyelitis optica is a CNS inflammatory disorder that predominantly affects the optic nerves and spinal cord. Jarius and Wildemann review the latest experimental and clinical evidence that supports a direct role for antibodies to aquaporin-4—the most abundant water channel in the brain—in the imm...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
July 2010
|
| In: |
Nature reviews. Neurology
Year: 2010, Jahrgang: 6, Heft: 7, Pages: 383-392 |
| ISSN: | 1759-4766 |
| DOI: | 10.1038/nrneurol.2010.72 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nrneurol.2010.72 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nrneurol.2010.72 
|
| Verfasserangaben: | Sven Jarius, Brigitte Wildemann |
MARC
| LEADER | 00000caa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1853769762 | ||
| 003 | DE-627 | ||
| 005 | 20240311130636.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230727s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/nrneurol.2010.72 |2 doi | |
| 035 | |a (DE-627)1853769762 | ||
| 035 | |a (DE-599)KXP1853769762 | ||
| 035 | |a (OCoLC)1425874426 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Jarius, Sven |e VerfasserIn |0 (DE-588)1054615918 |0 (DE-627)791654818 |0 (DE-576)410367478 |4 aut | |
| 245 | 1 | 0 | |a AQP4 antibodies in neuromyelitis optica |b diagnostic and pathogenetic relevance |c Sven Jarius, Brigitte Wildemann |
| 264 | 1 | |c July 2010 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 27.07.2023 | ||
| 520 | |a Neuromyelitis optica is a CNS inflammatory disorder that predominantly affects the optic nerves and spinal cord. Jarius and Wildemann review the latest experimental and clinical evidence that supports a direct role for antibodies to aquaporin-4—the most abundant water channel in the brain—in the immunopathogenesis of this condition. The authors also evaluate the range of diagnostic tests that are currently available for the detection of these antibodies. | ||
| 650 | 4 | |a Diagnostic markers | |
| 650 | 4 | |a Multiple sclerosis | |
| 650 | 4 | |a Pathogenesis | |
| 700 | 1 | |a Wildemann, Brigitte |e VerfasserIn |0 (DE-588)110203844 |0 (DE-627)510150004 |0 (DE-576)171831330 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature reviews. Neurology |d London : Macmillan Publishers Limited, part of Springer Nature, 2009 |g 6(2010), 7 vom: Juli, Seite 383-392 |h Online-Ressource |w (DE-627)598789251 |w (DE-600)2491518-X |w (DE-576)327495812 |x 1759-4766 |7 nnas |a AQP4 antibodies in neuromyelitis optica diagnostic and pathogenetic relevance |
| 773 | 1 | 8 | |g volume:6 |g year:2010 |g number:7 |g month:07 |g pages:383-392 |g extent:10 |a AQP4 antibodies in neuromyelitis optica diagnostic and pathogenetic relevance |
| 856 | 4 | 0 | |u https://doi.org/10.1038/nrneurol.2010.72 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/nrneurol.2010.72 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230727 | ||
| 993 | |a Article | ||
| 994 | |a 2010 | ||
| 998 | |g 110203844 |a Wildemann, Brigitte |m 110203844:Wildemann, Brigitte |d 910000 |d 911100 |d 50000 |e 910000PW110203844 |e 911100PW110203844 |e 50000PW110203844 |k 0/910000/ |k 1/910000/911100/ |k 0/50000/ |p 2 |y j | ||
| 998 | |g 1054615918 |a Jarius, Sven |m 1054615918:Jarius, Sven |d 910000 |d 911100 |e 910000PJ1054615918 |e 911100PJ1054615918 |k 0/910000/ |k 1/910000/911100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1853769762 |e 4358158242 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Sven Jarius, Brigitte Wildemann"]},"relHost":[{"title":[{"partname":"Neurology","title":"Nature reviews","title_sort":"Nature reviews"}],"note":["Gesehen am 07.01.2014"],"titleAlt":[{"title":"Nature reviews / Neurology"}],"language":["eng"],"origin":[{"publisher":"Macmillan Publishers Limited, part of Springer Nature ; Nature Publ. Group","dateIssuedDisp":"2009-","dateIssuedKey":"2009","publisherPlace":"London ; New York, NY"}],"pubHistory":["5.2009,4 -"],"physDesc":[{"extent":"Online-Ressource"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"id":{"zdb":["2491518-X"],"issn":["1759-4766"],"eki":["598789251"]},"recId":"598789251","part":{"volume":"6","extent":"10","text":"6(2010), 7 vom: Juli, Seite 383-392","issue":"7","pages":"383-392","year":"2010"},"disp":"AQP4 antibodies in neuromyelitis optica diagnostic and pathogenetic relevanceNature reviews. Neurology"}],"person":[{"roleDisplay":"VerfasserIn","role":"aut","family":"Jarius","given":"Sven","display":"Jarius, Sven"},{"roleDisplay":"VerfasserIn","role":"aut","given":"Brigitte","family":"Wildemann","display":"Wildemann, Brigitte"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1853769762","title":[{"title":"AQP4 antibodies in neuromyelitis optica","subtitle":"diagnostic and pathogenetic relevance","title_sort":"AQP4 antibodies in neuromyelitis optica"}],"origin":[{"dateIssuedDisp":"July 2010","dateIssuedKey":"2010"}],"language":["eng"],"id":{"eki":["1853769762"],"doi":["10.1038/nrneurol.2010.72"]},"note":["Gesehen am 27.07.2023"],"physDesc":[{"extent":"10 S."}]} | ||
| SRT | |a JARIUSSVENAQP4ANTIBO2010 | ||