Update Breast Cancer 2023, Part 2, Advanced-stage breast cancer = Update Mammakarzinom 2023, Teil 2, Brustkrebs in fortgeschrittenen Krankheitsstadien
Breast cancer - metastatic - endocrine therapy - antibody drug conjugate - chemotherapy
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2023
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| In: |
Geburtshilfe und Frauenheilkunde
Year: 2023, Volume: 83, Issue: 6, Pages: 664-672 |
| ISSN: | 1438-8804 |
| DOI: | 10.1055/a-2074-0125 |
| Online Access: | Resolving-System, kostenfrei: https://doi.org/10.1055/a-2074-0125 Resolving-System, kostenfrei: https://doi.org/10.25673/109850 
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| Author Notes: | authors: Michael P. Lux, Christoph Thomssen, Andreas Schneeweiss [und viele weitere] |
MARC
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| 520 | |a Breast cancer - metastatic - endocrine therapy - antibody drug conjugate - chemotherapy | ||
| 520 | |a In recent years, a number of new therapies have led to advances in the treatment of patients with advanced breast carcinoma. These substances are mainly CDK4/6 inhibitors and other substances that can overcome endocrine resistance, oral selective estrogen receptor degraders, antibody drug conjugates (ADCs), and PARP inhibitors. This review summarizes and evaluates the latest study results that have been published in recent months. This includes the overall survival data of the Destiny-Breast03 study, the first analysis of the CAPItello-291 study, the comparison of CDK4/6 inhibitor treatment with chemotherapy in the first line of therapy (RIGHT Choice study), the first analysis of the Destiny-Breast02 study in the treatment setting after T-DM1 treatment, and the first analysis of the Serena-2 study. Most of these studies have the potential to significantly change the therapeutic landscape for patients with advanced breast carcinoma and show that the continued rapid development of new therapies is always producing new results. | ||
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