Enantio- and regioselective iridium-catalyzed allylic hydroxylation
The first enantioselective allylic hydroxylation to prepare branched allylic alcohols directly is described. Bicarbonate was used as nucleophile in conjunction with new single component Ir-catalysts, which are stable to air and water. Excellent regio- and enantioselectivities have been achieved with...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
January 28, 2011
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| In: |
Journal of the American Chemical Society
Year: 2011, Jahrgang: 133, Heft: 7, Pages: 2072-2075 |
| ISSN: | 1520-5126 |
| DOI: | 10.1021/ja109953v |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1021/ja109953v
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| Verfasserangaben: | Martin Gärtner, Steffen Mader, Kai Seehafer, and Günter Helmchen |
| Zusammenfassung: | The first enantioselective allylic hydroxylation to prepare branched allylic alcohols directly is described. Bicarbonate was used as nucleophile in conjunction with new single component Ir-catalysts, which are stable to air and water. Excellent regio- and enantioselectivities have been achieved with a representative set of substrates. |
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| Beschreibung: | Gesehen am 07.08.2023 |
| Beschreibung: | Online Resource |
| ISSN: | 1520-5126 |
| DOI: | 10.1021/ja109953v |