Group-specific cellular metabolism in Medulloblastoma

Cancer metabolism influences multiple aspects of tumorigenesis and causes diversity across malignancies. Although comprehensive research has extended our knowledge of molecular subgroups in medulloblastoma (MB), discrete analysis of metabolic heterogeneity is currently lacking. This study seeks to i...

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Main Authors: Funke, Viktoria (Author) , Walter, Carolin (Author) , Melcher, Viktoria (Author) , Wei, Lanying (Author) , Sandmann, Sarah (Author) , Hotfilder, Marc (Author) , Varghese, Julian (Author) , Jäger, Natalie (Author) , Kool, Marcel (Author) , Jones, David T. W. (Author) , Pfister, Stefan (Author) , Milde, Till (Author) , Mynarek, Martin (Author) , Rutkowski, Stefan (Author) , Seggewiß, Jochen (Author) , Jeising, Daniela (Author) , de Faria, Flavia W. (Author) , Marquardt, Thorsten (Author) , Albert, Thomas (Author) , Schüller, Ulrich (Author) , Kerl, Kornelius (Author)
Format: Article (Journal)
Language:English
Published: 05 June 2023
In: Journal of translational medicine
Year: 2023, Volume: 21, Pages: 1-16
ISSN:1479-5876
DOI:10.1186/s12967-023-04211-6
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12967-023-04211-6
Verlag, kostenfrei, Volltext: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-023-04211-6
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Author Notes:Viktoria L.E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, Julian Varghese, Natalie Jäger, Marcel Kool, David T.W. Jones, Stefan M. Pfister, Till Milde, Martin Mynarek, Stefan Rutkowski, Jochen Seggewiss, Daniela Jeising, Flavia W. de Faria, Thorsten Marquardt, Thomas K. Albert, Ulrich Schüller and Kornelius Kerl
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Summary:Cancer metabolism influences multiple aspects of tumorigenesis and causes diversity across malignancies. Although comprehensive research has extended our knowledge of molecular subgroups in medulloblastoma (MB), discrete analysis of metabolic heterogeneity is currently lacking. This study seeks to improve our understanding of metabolic phenotypes in MB and their impact on patients’ outcomes.
Item Description:Gesehen am 21.11.2023
Physical Description:Online Resource
ISSN:1479-5876
DOI:10.1186/s12967-023-04211-6