Transient global amnesia with unexpected clinical and radiological findings: a case series and systematic review
Background - Transient global amnesia (TGA) represents a benign neurological syndrome of unknown pathophysiology, often accompanied by vanishing hippocampal punctate diffusion-weighted imaging lesions (HPDL). The literature suggests that TGA may present with unusual features. This study analyses aty...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
15 October 2022
|
| In: |
Journal of the neurological sciences
Year: 2022, Jahrgang: 441, Pages: 1-7 |
| ISSN: | 1878-5883 |
| DOI: | 10.1016/j.jns.2022.120349 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jns.2022.120349 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0022510X22002118 
|
| Verfasserangaben: | Silvio Piffer, Stefania Nannoni, Francesco Maulucci, Valérie Beaud, Olivier Rouaud, Alex Förster, Carlo W. Cereda, Philippe Maeder, Patrik Michel |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1856827453 | ||
| 003 | DE-627 | ||
| 005 | 20240307084922.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230822s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.jns.2022.120349 |2 doi | |
| 035 | |a (DE-627)1856827453 | ||
| 035 | |a (DE-599)KXP1856827453 | ||
| 035 | |a (OCoLC)1425216994 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Piffer, Silvio |e VerfasserIn |0 (DE-588)1299825095 |0 (DE-627)1856827585 |4 aut | |
| 245 | 1 | 0 | |a Transient global amnesia with unexpected clinical and radiological findings |b a case series and systematic review |c Silvio Piffer, Stefania Nannoni, Francesco Maulucci, Valérie Beaud, Olivier Rouaud, Alex Förster, Carlo W. Cereda, Philippe Maeder, Patrik Michel |
| 264 | 1 | |c 15 October 2022 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online verfügbar: 23 July 2022, Artikelversion: 6 August 2022 | ||
| 500 | |a Gesehen am 22.08.2023 | ||
| 520 | |a Background - Transient global amnesia (TGA) represents a benign neurological syndrome of unknown pathophysiology, often accompanied by vanishing hippocampal punctate diffusion-weighted imaging lesions (HPDL). The literature suggests that TGA may present with unusual features. This study analyses atypical clinical and radiological manifestations of patients with TGA and/or HPDL. - Methods - We retrospectively reviewed patients with atypical clinical or radiological presentations of TGA and/or HPDL in three neurology centers. We also performed a systematic review of literature using predefined search terms. Results were classified as: A) Atypical clinical manifestations of TGA (such as amnesia with additional manifestations, or only non-amnesic manifestations); B) Atypical radiological manifestations of clinically typical TGA. - Results - We identified 83 patients: 18 in our centres (median age 63.5years, 39% female) and 65 in the literature. In group A, 43 patients presented atypical clinical manifestations such as TGA with added transitory cognitive or sensory-motor deficits, seizures, headaches, but also non-amnesic presentations associated with HPDL and incidental HPDL without symptoms. In group B, 40 patients with typical clinical TGA showed extra-hippocampal punctate diffusion lesions (E-HPDL) which disappeared on follow-up imaging. Using clinical and radiological manifestations, we classified these patients into different categories describing a “TGA-PDL spectrum”. - Conclusions - TGA may have atypical clinical manifestations despite typical neuroimaging and patients with typical TGA may show vanishing extra-hippocampal punctate diffusion lesions. TGA, related clinical manifestations, and vanishing punctate diffusion lesions should be considered part of a larger “TGA-PDL spectrum”, allowing for better diagnosis of typical and atypical cases and stimulating further studies. | ||
| 650 | 4 | |a Amnesia | |
| 650 | 4 | |a Atypical transient global amnesia | |
| 650 | 4 | |a Hippocampal punctate diffusion lesion | |
| 650 | 4 | |a Magnetic resonance imaging | |
| 650 | 4 | |a Transient global amnesia | |
| 700 | 1 | |a Nannoni, Stefania |e VerfasserIn |4 aut | |
| 700 | 1 | |a Maulucci, Francesco |e VerfasserIn |4 aut | |
| 700 | 1 | |a Beaud, Valérie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rouaud, Olivier |e VerfasserIn |4 aut | |
| 700 | 1 | |a Förster, Alex |d 1978- |e VerfasserIn |0 (DE-588)132396971 |0 (DE-627)521958644 |0 (DE-576)299120112 |4 aut | |
| 700 | 1 | |a Cereda, Carlo W. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Maeder, Philippe |e VerfasserIn |4 aut | |
| 700 | 1 | |a Michel, Patrik |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of the neurological sciences |d Amsterdam [u.a.] : Elsevier Science, 1964 |g 441(2022) vom: Okt., Artikel-ID 120349, Seite 1-7 |h Online-Ressource |w (DE-627)306661152 |w (DE-600)1500645-1 |w (DE-576)081986742 |x 1878-5883 |7 nnas |a Transient global amnesia with unexpected clinical and radiological findings a case series and systematic review |
| 773 | 1 | 8 | |g volume:441 |g year:2022 |g month:10 |g elocationid:120349 |g pages:1-7 |g extent:7 |a Transient global amnesia with unexpected clinical and radiological findings a case series and systematic review |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.jns.2022.120349 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S0022510X22002118 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230822 | ||
| 993 | |a Article | ||
| 994 | |a 2022 | ||
| 998 | |g 132396971 |a Förster, Alex |m 132396971:Förster, Alex |d 60000 |d 63000 |e 60000PF132396971 |e 63000PF132396971 |k 0/60000/ |k 1/60000/63000/ |p 6 | ||
| 999 | |a KXP-PPN1856827453 |e 4368621980 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Online verfügbar: 23 July 2022, Artikelversion: 6 August 2022","Gesehen am 22.08.2023"],"recId":"1856827453","type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"subtitle":"a case series and systematic review","title_sort":"Transient global amnesia with unexpected clinical and radiological findings","title":"Transient global amnesia with unexpected clinical and radiological findings"}],"person":[{"display":"Piffer, Silvio","given":"Silvio","role":"aut","roleDisplay":"VerfasserIn","family":"Piffer"},{"family":"Nannoni","display":"Nannoni, Stefania","given":"Stefania","role":"aut","roleDisplay":"VerfasserIn"},{"family":"Maulucci","display":"Maulucci, Francesco","given":"Francesco","role":"aut","roleDisplay":"VerfasserIn"},{"family":"Beaud","display":"Beaud, Valérie","given":"Valérie","roleDisplay":"VerfasserIn","role":"aut"},{"family":"Rouaud","given":"Olivier","role":"aut","roleDisplay":"VerfasserIn","display":"Rouaud, Olivier"},{"family":"Förster","display":"Förster, Alex","given":"Alex","role":"aut","roleDisplay":"VerfasserIn"},{"family":"Cereda","roleDisplay":"VerfasserIn","role":"aut","given":"Carlo W.","display":"Cereda, Carlo W."},{"family":"Maeder","roleDisplay":"VerfasserIn","role":"aut","given":"Philippe","display":"Maeder, Philippe"},{"family":"Michel","roleDisplay":"VerfasserIn","role":"aut","given":"Patrik","display":"Michel, Patrik"}],"language":["eng"],"origin":[{"dateIssuedDisp":"15 October 2022","dateIssuedKey":"2022"}],"name":{"displayForm":["Silvio Piffer, Stefania Nannoni, Francesco Maulucci, Valérie Beaud, Olivier Rouaud, Alex Förster, Carlo W. Cereda, Philippe Maeder, Patrik Michel"]},"id":{"eki":["1856827453"],"doi":["10.1016/j.jns.2022.120349"]},"physDesc":[{"extent":"7 S."}],"relHost":[{"type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["1.1964 -"],"note":["Gesehen am 20.02.20","Ungezählte Beil.: Supplement"],"part":{"text":"441(2022) vom: Okt., Artikel-ID 120349, Seite 1-7","pages":"1-7","year":"2022","extent":"7","volume":"441"},"recId":"306661152","id":{"zdb":["1500645-1"],"eki":["306661152"],"issn":["1878-5883"]},"disp":"Transient global amnesia with unexpected clinical and radiological findings a case series and systematic reviewJournal of the neurological sciences","language":["eng"],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"Amsterdam [u.a.]","dateIssuedKey":"1964","publisher":"Elsevier Science","dateIssuedDisp":"1964-"}],"title":[{"subtitle":"official journal of the World Federation of Neurology","title_sort":"Journal of the neurological sciences","title":"Journal of the neurological sciences"}]}]} | ||
| SRT | |a PIFFERSILVTRANSIENTG1520 | ||