Association between aerobic fitness and the functional connectome in patients with schizophrenia

Schizophrenia is accompanied by widespread alterations in static functional connectivity associated with symptom severity and cognitive deficits. Improvements in aerobic fitness have been demonstrated to ameliorate symptomatology and cognition in people with schizophrenia, but the intermediary role...

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Main Authors: Röll, Lukas (Author) , Maurus, Isabel (Author) , Keeser, Daniel (Author) , Karali, Temmuz (Author) , Papazov, Boris (Author) , Hasan, Alkomiet (Author) , Schmitt, Andrea (Author) , Papazova, Irina (Author) , Lembeck, Moritz (Author) , Hirjak, Dusan (Author) , Sykorova, Eliska (Author) , Thieme, Cristina E. (Author) , Muenz, Susanne (Author) , Seitz, Valentina (Author) , Greska, David (Author) , Campana, Mattia (Author) , Wagner, Elias (Author) , Loehrs, Lisa (Author) , Stoecklein, Sophia (Author) , Ertl-Wagner, Birgit (Author) , Poemsl, Johannes (Author) , Roeh, Astrid (Author) , Malchow, Berend (Author) , Keller-Varady, Katriona (Author) , Meyer-Lindenberg, Andreas (Author) , Falkai, Peter (Author)
Format: Article (Journal)
Language:English
Published: 30 April 2022
In: European archives of psychiatry and clinical neuroscience
Year: 2022, Volume: 272, Issue: 7, Pages: 1253-1272
ISSN:1433-8491
DOI:10.1007/s00406-022-01411-x
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00406-022-01411-x
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00406-022-01411-x
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Author Notes:Lukas Roell, Isabel Maurus, Daniel Keeser, Temmuz Karali, Boris Papazov, Alkomiet Hasan, Andrea Schmitt, Irina Papazova, Moritz Lembeck, Dusan Hirjak, Eliska Sykorova, Cristina E. Thieme, Susanne Muenz, Valentina Seitz, David Greska, Mattia Campana, Elias Wagner, Lisa Loehrs, Sophia Stoecklein, Birgit Ertl-Wagner, Johannes Poemsl, Astrid Roeh, Berend Malchow, Katriona Keller-Varady, Andreas Meyer-Lindenberg, Peter Falkai
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Summary:Schizophrenia is accompanied by widespread alterations in static functional connectivity associated with symptom severity and cognitive deficits. Improvements in aerobic fitness have been demonstrated to ameliorate symptomatology and cognition in people with schizophrenia, but the intermediary role of macroscale connectivity patterns remains unknown.
Item Description:Gesehen am 22.08.2023
Physical Description:Online Resource
ISSN:1433-8491
DOI:10.1007/s00406-022-01411-x