EGF receptor modulates HEV entry in human hepatocytes
Being the most common cause of acute viral hepatitis with >20 million cases per year and 70,000 deaths annually, HEV presents a long-neglected and underinvestigated health burden. Although the entry process of viral particles is an attractive target for pharmacological intervention, druggable hos...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
February 7, 2023
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| In: |
Hepatology
Year: 2023, Jahrgang: 77, Heft: 6, Pages: 2104-2117 |
| ISSN: | 1527-3350 |
| DOI: | 10.1097/HEP.0000000000000308 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/HEP.0000000000000308 Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/hep/fulltext/2023/06000/egf_receptor_modulates_hev_entry_in_human.24.aspx 
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| Verfasserangaben: | Jil A. Schrader, Thomas L. Burkard, Yannick Brüggemann, André Gömer, Toni L. Meister, Rebecca M. Fu, Ann-Kathrin Mehnert, Viet L. Dao Thi, Patrick Behrendt, David Durantel, Ruth Broering, Florian W.R. Vondran, Daniel Todt, Volker Kinast, Eike Steinmann |
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| 520 | |a Being the most common cause of acute viral hepatitis with >20 million cases per year and 70,000 deaths annually, HEV presents a long-neglected and underinvestigated health burden. Although the entry process of viral particles is an attractive target for pharmacological intervention, druggable host factors to restrict HEV entry have not been identified so far. ... | ||
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