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RadioImmunotherapy for adenoid cystic carcinoma: a single-institution series of combined treatment with cetuximab

Local control in adjuvant/definitive RT of adenoid cystic carcinoma (ACC) is largely dose-dependent. However, some clinical situations do not allow application of tumouricidal doses (i.e. re-irradiation) hence radiation sensitization by exploitation of high endothelial growth factor receptor (EGFR)-...

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Bibliographische Detailangaben
Hauptverfasser: Jensen, Alexandra (VerfasserIn) , Krauß, Jürgen (VerfasserIn) , Weichert, Wilko (VerfasserIn) , Debus, Jürgen (VerfasserIn) , Münter, Marc (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 03 November 2010
In: Radiation oncology
Year: 2010, Jahrgang: 5, Pages: 1-8
ISSN:1748-717X
DOI:10.1186/1748-717X-5-102
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1748-717X-5-102
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Verfasserangaben:Alexandra D. Jensen, Jürgen Krauss, Wilko Weichert, Jürgen Debus, Marc W. Münter
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Zusammenfassung:Local control in adjuvant/definitive RT of adenoid cystic carcinoma (ACC) is largely dose-dependent. However, some clinical situations do not allow application of tumouricidal doses (i.e. re-irradiation) hence radiation sensitization by exploitation of high endothelial growth factor receptor (EGFR)-expression in ACC seems beneficial. This is a single-institution experience of combined radioimmunotherapy (RIT) with the EGFR-inhibitor cetuximab.
Beschreibung:Gesehen am 24.08.2023
Beschreibung:Online Resource
ISSN:1748-717X
DOI:10.1186/1748-717X-5-102

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