Cover Image

A BRCA1 promoter variant (rs11655505) and breast cancer risk

A study of Chinese women recently suggested that the minor allele of rs11655505 in the BRCA1 promoter (c.-2265C→T) increases promoter activity and has a protective effect on breast cancer risk. - We genotyped rs11655505 in 2912 female breast cancer cases and 2783 unaffected female controls from four...

Full description

Saved in:
Bibliographic Details
Main Authors: Verderio, Paolo (Author) , Pizzamiglio, Sara (Author) , Southey, Melissa C. (Author) , Spurdle, Amanda B. (Author) , Hopper, John L. (Author) , Chen, Xiaoqing (Author) , Beesley, Jonathan (Author) , Schmutzler, Rita K. (Author) , Engel, Christoph (Author) , Burwinkel, Barbara (Author) , Bugert, Peter (Author) , Ficarazzi, Filomena (Author) , Manoukian, Siranoush (Author) , Barile, Monica (Author) , Wappenschmidt, Barbara (Author) , Chenevix-Trench, Georgia (Author) , Radice, Paolo (Author) , Peterlongo, Paolo (Author)
Corporate Author: Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (Author)
Format: Article (Journal)
Language:English
Published: April 22, 2010
In: Journal of medical genetics
Year: 2010, Volume: 47, Issue: 4, Pages: 268-270
ISSN:1468-6244
DOI:10.1136/jmg.2009.073544
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1136/jmg.2009.073544
Verlag, lizenzpflichtig, Volltext: https://jmg.bmj.com/content/47/4/268
Get full text
Author Notes:Paolo Verderio, Sara Pizzamiglio, Melissa C. Southey, Amanda B. Spurdle, John L. Hopper, Xiaoqing Chen, Jonathan Beesley, Australian Ovarian Cancer Study Group, kConFab, Rita K. Schmutzler, Christoph Engel, Barbara Burwinkel, Peter Bugert, Filomena Ficarazzi, Siranoush Manoukian, Monica Barile, Barbara Wappenschmidt, Georgia Chenevix-Trench, Paolo Radice, Paolo Peterlongo
Description
Summary:A study of Chinese women recently suggested that the minor allele of rs11655505 in the BRCA1 promoter (c.-2265C→T) increases promoter activity and has a protective effect on breast cancer risk. - We genotyped rs11655505 in 2912 female breast cancer cases and 2783 unaffected female controls from four Caucasian breast cancer studies.
Item Description:Australian Ovarian Cancer Study Group: Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia and Queensland Institute of Medical Research, Brisbane, Queensland, Australia
Gesehen am 05.09.2023
Physical Description:Online Resource
ISSN:1468-6244
DOI:10.1136/jmg.2009.073544

Similar Items