Effects of inosine on reperfusion injury after cardiopulmonary bypass
Inosine, a break-down product of adenosine has been recently shown to exert inodilatory and anti-inflammatory properties. Furthermore inosine might be a key substrate of pharmacological post-conditioning. In the present pre-clinical study, we investigated the effects of inosine on cardiac function d...
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| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
8 November 2010
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| In: |
Journal of cardiothoracic surgery
Year: 2010, Jahrgang: 5, Pages: 1-6 |
| ISSN: | 1749-8090 |
| DOI: | 10.1186/1749-8090-5-106 |
| Online-Zugang: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/1749-8090-5-106 Verlag, kostenfrei, Volltext: https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-5-106 |
| Verfasserangaben: | Gábor Veres, Tamás Radovits, Leila Seres, Ferenc Horkay, Matthias Karck, Gábor Szabó |
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| 520 | |a Inosine, a break-down product of adenosine has been recently shown to exert inodilatory and anti-inflammatory properties. Furthermore inosine might be a key substrate of pharmacological post-conditioning. In the present pre-clinical study, we investigated the effects of inosine on cardiac function during reperfusion in an experimental model of cardioplegic arrest and extracorporal circulation. | ||
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