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Lower incidence of cytomegalovirus infection with everolimus versus mycophenolate mofetil in de novo cardiac transplant recipients: a randomized, multicenter study

Cytomegalovirus (CMV) is a major cause of infectious complications following cardiac transplantation, severely affecting short- and long-term outcomes. A 12-month, multicenter, randomized, open-label study in de novo cardiac transplant patients was undertaken to compare the efficacy, renal function,...

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Main Authors: Viganò, Mario (Author) , Dengler, Thomas (Author) , Mattei, M. F.. (Author) , Poncelet, A. (Author) , Vanhaecke, J. (Author) , Vermes, E. (Author) , Kleinloog, R. (Author) , Li, Y. (Author) , Gezahegen, Y. (Author) , Delgado, J. F. (Author)
Format: Article (Journal)
Language:English
Published: 20 January 2010
In: Transplant infectious disease
Year: 2010, Volume: 12, Issue: 1, Pages: 23-30
ISSN:1399-3062
DOI:10.1111/j.1399-3062.2009.00448.x
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1111/j.1399-3062.2009.00448.x
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-3062.2009.00448.x
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Author Notes:M. Viganò, T. Dengler, M.F. Mattei, A. Poncelet, J. Vanhaecke, E. Vermes, R. Kleinloog, Y. Li, Y. Gezahegen, J.F. Delgado, on behalf of the RAD A2411 Study Investigators
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Summary:Cytomegalovirus (CMV) is a major cause of infectious complications following cardiac transplantation, severely affecting short- and long-term outcomes. A 12-month, multicenter, randomized, open-label study in de novo cardiac transplant patients was undertaken to compare the efficacy, renal function, and safety of everolimus plus reduced cyclosporine versus mycophenolate mofetil (MMF) plus standard cyclosporine (ClinicalTrials.gov NCT00150046).
Item Description:Gesehen am 05.09.2023
Physical Description:Online Resource
ISSN:1399-3062
DOI:10.1111/j.1399-3062.2009.00448.x

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