Avoiding scar tissue formation of peripheral nerves with the help of an acellular collagen matrix
Extensive scar tissue formation after peripheral nerve injury or surgery is a common problem. To avoid perineural scarring, implanting a mechanical barrier protecting the nerve from inflammation processes in the perineural environment has shown promising results for functional recovery. This study i...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
August 4, 2023
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| In: |
PLOS ONE
Year: 2023, Jahrgang: 18, Heft: 8, Pages: 1-16 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0289677 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1371/journal.pone.0289677 Verlag, kostenfrei, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0289677 
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| Verfasserangaben: | Martin Aman, Maximilian Mayrhofer-Schmid, Daniel Schwarz, Martin Bendszus, Simeon C. Daeschler, Tess Klemm, Ulrich Kneser, Leila Harhaus, Arne H. Boecker |
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| 520 | |a Extensive scar tissue formation after peripheral nerve injury or surgery is a common problem. To avoid perineural scarring, implanting a mechanical barrier protecting the nerve from inflammation processes in the perineural environment has shown promising results for functional recovery. This study investigates the potential of an acellular collagen-elastin matrix wrapped around a peripheral nerve after induction of scar tissue formation. | ||
| 650 | 4 | |a Collagens | |
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| 650 | 4 | |a Scars | |
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| 650 | 4 | |a Surgical and invasive medical procedures | |
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