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Avoiding scar tissue formation of peripheral nerves with the help of an acellular collagen matrix

Extensive scar tissue formation after peripheral nerve injury or surgery is a common problem. To avoid perineural scarring, implanting a mechanical barrier protecting the nerve from inflammation processes in the perineural environment has shown promising results for functional recovery. This study i...

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Hauptverfasser: Aman, Martin (VerfasserIn) , Mayrhofer-Schmid, Maximilian (VerfasserIn) , Schwarz, Daniel (VerfasserIn) , Bendszus, Martin (VerfasserIn) , Däschler, Simeon C. (VerfasserIn) , Klemm, Tess (VerfasserIn) , Kneser, Ulrich (VerfasserIn) , Harhaus-Wähner, Leila (VerfasserIn) , Böcker, Arne Hendrik (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: August 4, 2023
In: PLOS ONE
Year: 2023, Jahrgang: 18, Heft: 8, Pages: 1-16
ISSN:1932-6203
DOI:10.1371/journal.pone.0289677
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1371/journal.pone.0289677
Verlag, kostenfrei, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0289677
Volltext
Verfasserangaben:Martin Aman, Maximilian Mayrhofer-Schmid, Daniel Schwarz, Martin Bendszus, Simeon C. Daeschler, Tess Klemm, Ulrich Kneser, Leila Harhaus, Arne H. Boecker
Beschreibung
Zusammenfassung:Extensive scar tissue formation after peripheral nerve injury or surgery is a common problem. To avoid perineural scarring, implanting a mechanical barrier protecting the nerve from inflammation processes in the perineural environment has shown promising results for functional recovery. This study investigates the potential of an acellular collagen-elastin matrix wrapped around a peripheral nerve after induction of scar tissue formation.
Beschreibung:Gesehen am 19.12.2023
Beschreibung:Online Resource
ISSN:1932-6203
DOI:10.1371/journal.pone.0289677

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