Reduced immune effector cell NKG2D expression and increased levels of soluble NKG2D ligands in multiple myeloma may not be causally linked
There is limited understanding of the dysregulation of the innate immune system in multiple myeloma (MM). We analysed the expression of the activating receptor NKG2D on NK cells and T cells of MM patients and investigated the impact of soluble versus membrane-bound NKG2D ligands on the expression of...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2010
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| In: |
Cancer immunology immunotherapy
Year: 2010, Jahrgang: 59, Heft: 6, Pages: 829-839 |
| ISSN: | 1432-0851 |
| DOI: | 10.1007/s00262-009-0807-3 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00262-009-0807-3 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00262-009-0807-3 |
| Verfasserangaben: | Marie von Lilienfeld-Toal, Susanne Frank, Christiane Leyendecker, Sylvia Feyler, Sarah Jarmin, Ruth Morgan, Axel Glasmacher, Angela Märten, Ingo G.H. Schmidt-Wolf, Peter Brossart, Gordon Cook |
| Zusammenfassung: | There is limited understanding of the dysregulation of the innate immune system in multiple myeloma (MM). We analysed the expression of the activating receptor NKG2D on NK cells and T cells of MM patients and investigated the impact of soluble versus membrane-bound NKG2D ligands on the expression of NKG2D. |
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| Beschreibung: | Online veröffentlicht am 19. Dezember 2009 Gesehen am 14.09.2023 |
| Beschreibung: | Online Resource |
| ISSN: | 1432-0851 |
| DOI: | 10.1007/s00262-009-0807-3 |