Relationship between fasting glucose and retinopathy for diagnosis of diabetes: results from a population-based study in urban and rural China
Purpose: - The purpose of this study was to assess the relationship between the fasting plasma glucose cutoff of 7 mmol/L and the presence of retinopathy in a population in China. - Methods: - The Beijing Eye Study 2006 is a population-based study, which included 3,251 subjects aged ≥45...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
[September 2010]
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| In: |
Retina
Year: 2010, Jahrgang: 30, Heft: 8, Pages: 1223-1227 |
| ISSN: | 1539-2864 |
| DOI: | 10.1097/IAE.0b013e3181ce74ae |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/IAE.0b013e3181ce74ae Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/retinajournal/abstract/2010/09000/relationship_between_fasting_glucose_and.11.aspx 
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| Verfasserangaben: | Jost B. Jonas, Liang Xu, Xi Wei Xie, Ya Xing Wang |
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| 245 | 1 | 0 | |a Relationship between fasting glucose and retinopathy for diagnosis of diabetes |b results from a population-based study in urban and rural China |c Jost B. Jonas, Liang Xu, Xi Wei Xie, Ya Xing Wang |
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| 520 | |a Purpose: - The purpose of this study was to assess the relationship between the fasting plasma glucose cutoff of 7 mmol/L and the presence of retinopathy in a population in China. - Methods: - The Beijing Eye Study 2006 is a population-based study, which included 3,251 subjects aged ≥45 years. By using fundus photographs, retinopathy was assessed according to the Early Treatment of Diabetic Retinopathy Study. - Results: - The correlation between fasting plasma glucose concentration and retinopathy suggested a continuous relation instead of a uniform glycemic threshold for prevalent retinopathy. For the diabetes plasma glucose concentration cutoffs of 7.0 mmol/L, 5.6 mmol/L, and 7.8 mmol/L to differentiate between subjects with or without retinopathy, the sensitivities were 18.8%, 44.0%, and 15.4%, respectively, and the specificities were 94.3%, 73.8%, and 96.6%, respectively. After excluding subjects with known diabetes and/or subjects on antidiabetic treatment, the sensitivities of diabetes plasma glucose concentration cutoffs of 7.0 mmol/L, 5.6 mmol/L, and 7.8 mmol/L to differentiate between subjects with or without retinopathy were 7.9%, 34.2%, and 6.3%, respectively, and the specificities were 96.5%, 77.1%, and 98.1%, respectively. - Conclusion: - Confirming a recent study from Australian and North American populations, the results suggest that also for the Chinese population, a uniform glycemic threshold for prevalent retinopathy does not exist. | ||
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