Sudden death of an immunocompetent young adult caused by novel (swine origin) influenza A/H1N1-associated myocarditis
The main cause of death from novel (swine origin) influenza A/H1N1 infection is acute respiratory distress syndrome. Most fatal cases are immunocompromised patients or patients with a severe underlying disease. Here, we report a fatal case of acute interstitial myocarditis associated with novel infl...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
14 January 2011
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| In: |
Virchows Archiv
Year: 2011, Jahrgang: 458, Heft: 3, Pages: 371-376 |
| ISSN: | 1432-2307 |
| DOI: | 10.1007/s00428-010-1035-0 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00428-010-1035-0
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| Verfasserangaben: | Georg Gdynia, Paul Schnitzler, Eva Brunner, Reinhard Kandolf, Hendrik Bläker, Edith Daum, Philipp Schnabel, Peter Schirmacher, Wilfried Roth |
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| 245 | 1 | 0 | |a Sudden death of an immunocompetent young adult caused by novel (swine origin) influenza A/H1N1-associated myocarditis |c Georg Gdynia, Paul Schnitzler, Eva Brunner, Reinhard Kandolf, Hendrik Bläker, Edith Daum, Philipp Schnabel, Peter Schirmacher, Wilfried Roth |
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| 520 | |a The main cause of death from novel (swine origin) influenza A/H1N1 infection is acute respiratory distress syndrome. Most fatal cases are immunocompromised patients or patients with a severe underlying disease. Here, we report a fatal case of acute interstitial myocarditis associated with novel influenza A/H1N1 infection in an immunocompetent young woman. A previously healthy 18-year-old woman experienced malaise, diarrhea, and fever for several days prior to a sudden collapse at home. Autopsy revealed a predominantly lymphocytic myocarditis in the absence of a significant respiratory tract infection. Infection with novel (swine origin) influenza A/H1N1 was confirmed by PCR analysis of blood as well as myocardial tissue. Influenza-caused diarrhea with consecutive hypokalemia potentially contributed to the fatal outcome of the myocarditis, characterized by ventricular fibrillation. In conclusion, sudden death by myocarditis may be a rare complication of novel influenza A/H1N1 infection in otherwise healthy individuals, even in the absence of significant respiratory tract infection. | ||
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