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2-hydroxyglutarate rides the cancer-immunity cycle

2-hydroxyglutarate (2HG) is a biproduct of the Krebs cycle, which exists in a D- and L- enantiomer and is structurally similar to α-ketoglutarate. Both 2HG enantiomers have been described to accumulate in diverse cancer and immune cells and can influence cell fate and function. While D-2HG was origi...

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Hauptverfasser: Foskolou, Iosifina (VerfasserIn) , Bunse, Lukas (VerfasserIn) , Van den Bossche, Jan (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: October 2023
In: Current opinion in biotechnology
Year: 2023, Jahrgang: 83, Pages: 1-7
ISSN:1879-0429
DOI:10.1016/j.copbio.2023.102976
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.copbio.2023.102976
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0958166923000861
Volltext
Verfasserangaben:Iosifina P Foskolou, Lukas Bunse, Jan Van den Bossche

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