Position paper: Rapid responses to steroids: current status and future prospects
Steroids exert their actions through several pathways. The classical genomic pathway, which involves binding of steroids to receptors and subsequent modulation of gene expression, is well characterized. Besides this, rapid actions of steroids have been shown to exist. Since 30 years, research on rap...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
01 May 2010
|
| In: |
European journal of endocrinology
Year: 2010, Jahrgang: 162, Heft: 5, Pages: 825-830 |
| ISSN: | 1479-683X |
| DOI: | 10.1530/EJE-09-1072 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1530/EJE-09-1072
|
| Verfasserangaben: | Alexandra Wendler, Elisabetta Baldi, Brian J Harvey, Angel Nadal, Anthony Norman and Martin Wehling |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1869154762 | ||
| 003 | DE-627 | ||
| 005 | 20240311121822.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231103s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1530/EJE-09-1072 |2 doi | |
| 035 | |a (DE-627)1869154762 | ||
| 035 | |a (DE-599)KXP1869154762 | ||
| 035 | |a (OCoLC)1425873028 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Wendler, Alexandra |d 1980- |e VerfasserIn |0 (DE-588)136872352 |0 (DE-627)694727954 |0 (DE-576)301319545 |4 aut | |
| 245 | 1 | 0 | |a Position paper: Rapid responses to steroids |b current status and future prospects |c Alexandra Wendler, Elisabetta Baldi, Brian J Harvey, Angel Nadal, Anthony Norman and Martin Wehling |
| 264 | 1 | |c 01 May 2010 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 03.11.2023 | ||
| 520 | |a Steroids exert their actions through several pathways. The classical genomic pathway, which involves binding of steroids to receptors and subsequent modulation of gene expression, is well characterized. Besides this, rapid actions of steroids have been shown to exist. Since 30 years, research on rapid actions of steroids is an emerging field of science. Today, rapid effects of steroids are well established, and are shown to exist for every type of steroid. The classical steroid receptors have been shown to be involved in rapid actions, but there is also strong evidence that unrelated structures mediate these rapid effects. Despite increasing knowledge about the mechanisms and structures which mediate these actions, there is still no unanimous acceptance of this category. This article briefly reviews the history of the field including current controversies and challenges. It is not meant as a broad review of literature, but should increase the awareness of the endocrinology society for rapid responses to steroids. As members of the organizing committee of the VI International Meeting on Rapid Responses to Steroid Hormones 2009, we propose a research agenda focusing on the identification of new receptoral structures and the identification of mechanisms of actions at physiological steroid concentrations. Additionally, efforts for the propagation of translational studies, which should finally lead to clinical benefit in the area of rapid steroid action research, should be intensified. | ||
| 700 | 1 | |a Baldi, Elisabetta |e VerfasserIn |4 aut | |
| 700 | 1 | |a Harvey, Brian J |e VerfasserIn |4 aut | |
| 700 | 1 | |a Nadal, Angel |e VerfasserIn |4 aut | |
| 700 | 1 | |a Norman, Anthony |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wehling, Martin |d 1957- |e VerfasserIn |0 (DE-588)129939331 |0 (DE-627)484463152 |0 (DE-576)297912577 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of endocrinology |d Oxford : Oxford University Press, 1994 |g 162(2010), 5 vom: Mai, Seite 825-830 |h Online-Ressource |w (DE-627)30151741X |w (DE-600)1485160-X |w (DE-576)079421466 |x 1479-683X |7 nnas |a Position paper: Rapid responses to steroids current status and future prospects |
| 773 | 1 | 8 | |g volume:162 |g year:2010 |g number:5 |g month:05 |g pages:825-830 |g extent:6 |a Position paper: Rapid responses to steroids current status and future prospects |
| 856 | 4 | 0 | |u https://doi.org/10.1530/EJE-09-1072 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20231103 | ||
| 993 | |a Article | ||
| 994 | |a 2010 | ||
| 998 | |g 129939331 |a Wehling, Martin |m 129939331:Wehling, Martin |d 60000 |d 65400 |e 60000PW129939331 |e 65400PW129939331 |k 0/60000/ |k 1/60000/65400/ |p 6 |y j | ||
| 998 | |g 136872352 |a Wendler, Alexandra |m 136872352:Wendler, Alexandra |d 60000 |d 65400 |d 60000 |e 60000PW136872352 |e 65400PW136872352 |e 60000PW136872352 |k 0/60000/ |k 1/60000/65400/ |k 0/60000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1869154762 |e 4401399250 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"6 S."}],"recId":"1869154762","type":{"bibl":"article-journal","media":"Online-Ressource"},"language":["eng"],"note":["Gesehen am 03.11.2023"],"title":[{"title":"Position paper: Rapid responses to steroids","title_sort":"Position paper: Rapid responses to steroids","subtitle":"current status and future prospects"}],"origin":[{"dateIssuedKey":"2010","dateIssuedDisp":"01 May 2010"}],"person":[{"family":"Wendler","role":"aut","given":"Alexandra","display":"Wendler, Alexandra"},{"display":"Baldi, Elisabetta","given":"Elisabetta","role":"aut","family":"Baldi"},{"display":"Harvey, Brian J","family":"Harvey","role":"aut","given":"Brian J"},{"role":"aut","given":"Angel","family":"Nadal","display":"Nadal, Angel"},{"display":"Norman, Anthony","role":"aut","given":"Anthony","family":"Norman"},{"family":"Wehling","given":"Martin","role":"aut","display":"Wehling, Martin"}],"relHost":[{"part":{"year":"2010","volume":"162","pages":"825-830","issue":"5","text":"162(2010), 5 vom: Mai, Seite 825-830","extent":"6"},"id":{"zdb":["1485160-X"],"eki":["30151741X"],"issn":["1479-683X"]},"pubHistory":["Volume 130, issue 1 (Jan 1994)-"],"titleAlt":[{"title":"EJE"},{"title":"European journal of endocrinology"},{"title":"official journal of the European Federation of Endocrine Societies"},{"title":"EJE"}],"disp":"Position paper: Rapid responses to steroids current status and future prospectsEuropean journal of endocrinology","recId":"30151741X","physDesc":[{"extent":"Online-Ressource"}],"title":[{"title":"European journal of endocrinology","title_sort":"European journal of endocrinology","subtitle":"EJE : clinical and translational endocrinology from around the globe"}],"note":["Gesehen am 21.08.25"],"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"publisherPlace":"Oxford ; Bristol","dateIssuedKey":"1994","dateIssuedDisp":"1994-","publisher":"Oxford University Press ; BioScientifica Ltd."}]}],"id":{"eki":["1869154762"],"doi":["10.1530/EJE-09-1072"]},"name":{"displayForm":["Alexandra Wendler, Elisabetta Baldi, Brian J Harvey, Angel Nadal, Anthony Norman and Martin Wehling"]}} | ||
| SRT | |a WENDLERALEPOSITIONPA0120 | ||