MRI predictors for the conversion from contrast-enhancing to iron rim multiple sclerosis lesions: original communication

In multiple sclerosis (MS), iron rim lesions (IRLs) are characterized by progressive tissue matrix damage. Therefore, early identification could represent an interesting target for therapeutic intervention to minimize evolving tissue damage. The aim of this study was to identify magnetic resonance i...

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Main Authors: Wenzel, Nicolas (Author) , Wittayer, Matthias Sebastian (Author) , Weber, Claudia Ellen (Author) , Schirmer, Lucas (Author) , Platten, Michael (Author) , Gass, Achim (Author) , Eisele, Philipp (Author)
Format: Article (Journal)
Language:English
Published: 25 March 2022
In: Journal of neurology
Year: 2022, Volume: 269, Issue: 8, Pages: 4414-4420
ISSN:1432-1459
DOI:10.1007/s00415-022-11082-2
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00415-022-11082-2
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00415-022-11082-2
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Author Notes:Nicolas Wenzel, Matthias Wittayer, Claudia E. Weber, Lucas Schirmer, Michael Platten, Achim Gass, Philipp Eisele
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Summary:In multiple sclerosis (MS), iron rim lesions (IRLs) are characterized by progressive tissue matrix damage. Therefore, early identification could represent an interesting target for therapeutic intervention to minimize evolving tissue damage. The aim of this study was to identify magnetic resonance imaging (MRI) parameters predicting the conversion from contrast-enhancing to IRLs.
Item Description:Gesehen am 07.11.2023
Physical Description:Online Resource
ISSN:1432-1459
DOI:10.1007/s00415-022-11082-2