Impact of guideline changes on adoption of hypofractionation and breast cancer patient characteristics in the randomized controlled HYPOSIB trial

Hypofractionated radiotherapy is the standard of care for adjuvant whole breast radiotherapy (RT). However, adoption has been slow. The indication for regional nodal irradiation has been expanded to include patients with 0-3 involved lymph nodes. We investigated the impact of the publication of the...

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Main Authors: Krug, David (Author) , Vonthein, Reinhard (Author) , Schreiber, Andreas (Author) , Boicev, Alexander D. (Author) , Zimmer, Jörg (Author) , Laubach, Reinhold (Author) , Weidner, Nicola (Author) , Dinges, Stefan (Author) , Hipp, Matthias (Author) , Schneider, Ralf (Author) , Weinstrauch, Evelyn (Author) , Martin, Thomas (Author) , Hörner-Rieber, Juliane (Author) , Olbrich, Denise (Author) , Illen, Alicia (Author) , Heßler, Nicole (Author) , König, Inke R. (Author) , Dellas, Kathrin (Author) , Dunst, Jürgen (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: Strahlentherapie und Onkologie
Year: 2021, Volume: 197, Issue: 9, Pages: 802-811
ISSN:1439-099X
DOI:10.1007/s00066-020-01730-9
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00066-020-01730-9
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Author Notes:David Krug, Reinhard Vonthein, Andreas Schreiber, Alexander D. Boicev, Jörg Zimmer, Reinhold Laubach, Nicola Weidner, Stefan Dinges, Matthias Hipp, Ralf Schneider, Evelyn Weinstrauch, Thomas Martin, Juliane Hörner-Rieber, Denise Olbrich, Alicia Illen, Nicole Heßler, Inke R. König, Kathrin Dellas, Jürgen Dunst
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Summary:Hypofractionated radiotherapy is the standard of care for adjuvant whole breast radiotherapy (RT). However, adoption has been slow. The indication for regional nodal irradiation has been expanded to include patients with 0-3 involved lymph nodes. We investigated the impact of the publication of the updated German S3 guidelines in 2017 on adoption of hypofractionation and enrollment of patients with lymph node involvement within a randomized controlled phase III trial.
Item Description:Online veröffentlicht: 15 Dezember 2020
Gesehen am 7.11.2023
Physical Description:Online Resource
ISSN:1439-099X
DOI:10.1007/s00066-020-01730-9