APP family member dimeric complexes are formed predominantly in synaptic compartments
The amyloid precursor protein (APP), a key player in Alzheimer’s disease (AD), is part of a larger gene family, including the APP like proteins APLP1 and APLP2. They share similar structures, form homo- and heterotypic dimers and exhibit overlapping functions.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
02 August 2023
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| In: |
Cell & bioscience
Year: 2023, Jahrgang: 13, Pages: 1-24 |
| ISSN: | 2045-3701 |
| DOI: | 10.1186/s13578-023-01092-6 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13578-023-01092-6 Verlag, kostenfrei, Volltext: https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-023-01092-6 
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| Verfasserangaben: | Sandra Schilling, Alexander August, Mathieu Meleux, Carolin Conradt, Luisa M. Tremmel, Sandra Teigler, Virginie Adam, Ulrike C. Müller, Edward H. Koo, Stefan Kins and Simone Eggert |
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| 520 | |a The amyloid precursor protein (APP), a key player in Alzheimer’s disease (AD), is part of a larger gene family, including the APP like proteins APLP1 and APLP2. They share similar structures, form homo- and heterotypic dimers and exhibit overlapping functions. | ||
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