An efficient one-pot synthesis of tetra-substituted pyrroles
The three-component reaction of primary amines, dialkyl acetylenedicarboxylates and β-nitrostyrene derivatives in the presence of Iron(III) chloride afforded 1,2,3,4-tetra-substituted pyrroles in high yields. These reactions could precede via domino Michael addition/cyclization process.
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
25 May 2011
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| In: |
Tetrahedron
Year: 2011, Jahrgang: 67, Heft: 30, Pages: 5415-5420 |
| ISSN: | 1464-5416 |
| DOI: | 10.1016/j.tet.2011.05.076 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.tet.2011.05.076 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0040402011007502 |
| Verfasserangaben: | Elmira Ghabraie, Saeed Balalaie, Morteza Bararjanian, Hamid Reza Bijanzadeh, Frank Rominger |
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| 520 | |a The three-component reaction of primary amines, dialkyl acetylenedicarboxylates and β-nitrostyrene derivatives in the presence of Iron(III) chloride afforded 1,2,3,4-tetra-substituted pyrroles in high yields. These reactions could precede via domino Michael addition/cyclization process. | ||
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